TY - JOUR
T1 - The Italian version of cognitive function instrument (CFI)
T2 - reliability and validity in a cohort of healthy elderly
AU - Chipi, Elena
AU - Frattini, Giulia
AU - Eusebi, Paolo
AU - Mollica, Anita
AU - D’Andrea, Katia
AU - Russo, Mirella
AU - Bernardelli, Alice
AU - Montanucci, Chiara
AU - Luchetti, Elisa
AU - Calabresi, Paolo
AU - Parnetti, Lucilla
PY - 2017/10/23
Y1 - 2017/10/23
N2 - The Alzheimer’s disease Cooperative Study (ADCS)-Cognitive Function Instrument (CFI) is a 14-item questionnaire administered to the subject and the referent, aimed at detecting early changes in cognitive and functional abilities in individuals without clinical impairment. It is used for monitoring annual variations in cognitive functioning in prevention trials. The aim of the present study was to validate the Italian version of the CFI. A consecutive series of 257 functionally independent subjects was recruited among relatives of patients or as volunteers. They were administered CFI and global cognition measurements: Mini-Mental Status Examination (MMSE) and Repeatable Battery for the Assessment of Neuropsychological Status (RBANS). The reliability and criterion validity were comparable to the original in both self- and partner-report. Similarly to what reported in the original version, we found a corrected item-total correlation ranging between 0.38 and 0.54 in self-report and between 0.33 and 0.64 in partner-report. Cronbach’s α was 0.77 (95% CI 0.72–0.83) in self-report and 0.78 (95% CI 0.73–0.84) in partner-report. Total partner- and self-report scores were significantly correlated (rS = 0.31, p < 0.001). CFI self-report and CFI total-score (partner + self-report) were negatively correlated with MMSE (rS = − 0.15, p = 0.022; rS = − 0.17, p = 0.008) and RBANS (rS = − 0.22, p < 0.001; rS = − 0.25, p < 0.001). Analogous trends were found in the partner score, with a correlation with RBANS (rS = − 0.17, p = 0.014) and MMSE (rS = − 0.11, p = 0.071). Our results support the reliability and validity of the Italian version of CFI. In order to definitely propose the use of CFI for tracking longitudinal changes of cognitive and functional abilities in subjects without clinical impairment, data from the follow-up of this cohort are needed.
AB - The Alzheimer’s disease Cooperative Study (ADCS)-Cognitive Function Instrument (CFI) is a 14-item questionnaire administered to the subject and the referent, aimed at detecting early changes in cognitive and functional abilities in individuals without clinical impairment. It is used for monitoring annual variations in cognitive functioning in prevention trials. The aim of the present study was to validate the Italian version of the CFI. A consecutive series of 257 functionally independent subjects was recruited among relatives of patients or as volunteers. They were administered CFI and global cognition measurements: Mini-Mental Status Examination (MMSE) and Repeatable Battery for the Assessment of Neuropsychological Status (RBANS). The reliability and criterion validity were comparable to the original in both self- and partner-report. Similarly to what reported in the original version, we found a corrected item-total correlation ranging between 0.38 and 0.54 in self-report and between 0.33 and 0.64 in partner-report. Cronbach’s α was 0.77 (95% CI 0.72–0.83) in self-report and 0.78 (95% CI 0.73–0.84) in partner-report. Total partner- and self-report scores were significantly correlated (rS = 0.31, p < 0.001). CFI self-report and CFI total-score (partner + self-report) were negatively correlated with MMSE (rS = − 0.15, p = 0.022; rS = − 0.17, p = 0.008) and RBANS (rS = − 0.22, p < 0.001; rS = − 0.25, p < 0.001). Analogous trends were found in the partner score, with a correlation with RBANS (rS = − 0.17, p = 0.014) and MMSE (rS = − 0.11, p = 0.071). Our results support the reliability and validity of the Italian version of CFI. In order to definitely propose the use of CFI for tracking longitudinal changes of cognitive and functional abilities in subjects without clinical impairment, data from the follow-up of this cohort are needed.
KW - Alzheimer’s disease
KW - CFI
KW - Italian validation
KW - Questionnaire
KW - Subjective cognitive decline
UR - http://www.scopus.com/inward/record.url?scp=85031906546&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85031906546&partnerID=8YFLogxK
U2 - 10.1007/s10072-017-3150-z
DO - 10.1007/s10072-017-3150-z
M3 - Article
AN - SCOPUS:85031906546
VL - 39
SP - 111
EP - 118
JO - Neurological Sciences
JF - Neurological Sciences
SN - 1590-1874
IS - 1
ER -