The Lambert-Eaton syndrome (LEMS) is a rare immunologic disease characterized by chronic asthenia. It is different from classic myasthenic syndrome in the target of its antibodies. One of the characteristics of LEMS is the association with small cells lung cancer; so it can be considered a paraneoplastic syndrome. The association with other histologic kinds of cancer is extremely rare. The case of a male patient is described, sixty-two years old, smoker, suffering from LEMS. He comes under our observation for neoplastic cells found in his expectorate. At the moment thorax-X-ray resulted negative. Among the made researches, FBS showed an extrinsic compression of the felt main bronchus and TAC total body the presence of two nodules in the left inferior lobe and mediastynic adenopathy too. Histologic exam of that neoformation showed an epidermoidal cancer. After this result we began antiblastic therapy; in this way a regression of the pulmonary opacity and an improvement of neurologic symptoms was obtained. In the presence of LEMS is very important to search for a below neoplasy, to make a precocious diagnosis.
|Translated title of the contribution||The Lambert-Eaton syndrome: A clinical case|
|Number of pages||4|
|Journal||Lotta Contro la Tuberculosi e le Malattie Polmonari Sociali|
|Publication status||Published - 1995|
ASJC Scopus subject areas
- Pulmonary and Respiratory Medicine