The level of cortical afferent inhibition in acute stroke correlates with long-term functional recovery in humans

Vincenzo Di Lazzaro, Paolo Profice, Fabio Pilato, Fioravante Capone, Federico Ranieri, Lucia Florio, Cesare Colosimo, Emanuele Pravatà, Patrizio Pasqualetti, Michele Dileone

Research output: Contribution to journalArticle

32 Citations (Scopus)

Abstract

Background and Purpose-: Using transcranial magnetic stimulation, we investigated short-interval intracortical inhibition and short-latency afferent inhibition in acute ischemic stroke. Methods-: We evaluated short-interval intracortical inhibition and short-latency afferent inhibition in the affected hemisphere and unaffected hemisphere in 16 patients and correlated electrophysiological parameters with outcome at 6 months. Results-: Affected hemisphere short-latency afferent inhibition was significantly reduced in patients, and short-latency afferent inhibition level correlated with functional outcome. Conclusions-: Reduced afferent inhibition in acute stroke correlates with long-term recovery.

Original languageEnglish
Pages (from-to)250-252
Number of pages3
JournalStroke
Volume43
Issue number1
DOIs
Publication statusPublished - Jan 2012

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Stroke
Transcranial Magnetic Stimulation

Keywords

  • GABA
  • transcranial magnetic stimulation

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Clinical Neurology
  • Advanced and Specialised Nursing

Cite this

Di Lazzaro, V., Profice, P., Pilato, F., Capone, F., Ranieri, F., Florio, L., ... Dileone, M. (2012). The level of cortical afferent inhibition in acute stroke correlates with long-term functional recovery in humans. Stroke, 43(1), 250-252. https://doi.org/10.1161/STROKEAHA.111.631085

The level of cortical afferent inhibition in acute stroke correlates with long-term functional recovery in humans. / Di Lazzaro, Vincenzo; Profice, Paolo; Pilato, Fabio; Capone, Fioravante; Ranieri, Federico; Florio, Lucia; Colosimo, Cesare; Pravatà, Emanuele; Pasqualetti, Patrizio; Dileone, Michele.

In: Stroke, Vol. 43, No. 1, 01.2012, p. 250-252.

Research output: Contribution to journalArticle

Di Lazzaro, V, Profice, P, Pilato, F, Capone, F, Ranieri, F, Florio, L, Colosimo, C, Pravatà, E, Pasqualetti, P & Dileone, M 2012, 'The level of cortical afferent inhibition in acute stroke correlates with long-term functional recovery in humans', Stroke, vol. 43, no. 1, pp. 250-252. https://doi.org/10.1161/STROKEAHA.111.631085
Di Lazzaro, Vincenzo ; Profice, Paolo ; Pilato, Fabio ; Capone, Fioravante ; Ranieri, Federico ; Florio, Lucia ; Colosimo, Cesare ; Pravatà, Emanuele ; Pasqualetti, Patrizio ; Dileone, Michele. / The level of cortical afferent inhibition in acute stroke correlates with long-term functional recovery in humans. In: Stroke. 2012 ; Vol. 43, No. 1. pp. 250-252.
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