The long-term prognostic significance of repeated blood pressure measurements in the elderly: SPAA (studio sulla pressione arteriosa nell'anziano) 10-year follow-up

Claudio Alli, Fausto Avanzini, Giuseppe Bettelli, Fabio Colombo, Valter Torri, Gianni Tognoni

Research output: Contribution to journalArticle

Abstract

Background: In young and middle-aged people, both systolic (SBP) and diastolic (DBP) blood pressure have a continuous, strong, and independent relationship with subsequent cardiovascular morbidity and mortality. These relationships are not well documented in older people and, until now, studies in the elderly do not provide homogeneous results on the importance of DBP compared with SBP as a cardiovascular risk factor. Objective: To determine whether SBP and DBP are independent indicators of mortality risk in the elderly. Design: An observational prospective cohort study to analyze the long-term prognostic significance of repeated SBP and DBP measurements in the elderly. Patients and Methods: A total of 3858 outpatients 65 years or older (mean age [SD], 72.9 [4.9] years, 43.5% men) were selected randomly by 444 Italian National Health Service general practitioners in 1983. The population was followed up for 10 years. Crude and adjusted incidence rates of total and cardiovascular mortality were analyzed for classes of SBP and DBP based on the values recorded at the 2 initial visits 1 week apart and those measured during the first 12 months of follow-up. Results: During the 10-year follow- up, 74 patients (1.9%) were lost to follow-up and 1561 (41.3%) died, 709 (45.4% of all deaths) from cardiovascular causes. A positive continuous, graded, strong, and independent association was observed with both total (P

Original languageEnglish
Pages (from-to)1205-1212
Number of pages8
JournalArchives of Internal Medicine
Volume159
Issue number11
DOIs
Publication statusPublished - Jun 14 1999

ASJC Scopus subject areas

  • Internal Medicine

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