The main determinants of nitrogen balance during total parenteral nutrition in critically ill injured patients

G. Iapichino, D. Radrizzani, M. Solca, A. Pesenti, L. Gattinoni, A. Ferro, L. Leoni, M. Langer, S. Vesconi, G. Damia

Research output: Contribution to journalArticlepeer-review

Abstract

Factors influencing nitrogen balance during total parenteral nutrition have been investigated in 34 critically ill injured patients studied during the first 6 days after trauma. Basal nitrogen balance was severely negative (-0.26±0.12 (SD) g·kg-1), but improved consistently during treatment. Nitrogen intake proved to be the major determinant of a positive, or less negative, nitrogen balance, only secondarily followed by total energy intake corrected to predicted basal energy expenditure, according to multiple regression analysis. The amount of non-protein calories and the non-protein calorie to nitrogen ratio appeared to have little significance on nitrogen balance, when corrected for the two former variables.

Original languageEnglish
Pages (from-to)251-254
Number of pages4
JournalIntensive Care Medicine
Volume10
Issue number5
DOIs
Publication statusPublished - Sep 1984

Keywords

  • Calorie intake
  • Injury
  • Nitrogen balance
  • Nitrogen intake
  • Total parenteral nutrition

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine

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