Abstract
Background: Venous thromboembolism (VTE) is a major health problem, with over one million events every year in Europe. However, there is a paucity of data on the current management in real life, including factors influencing treatment pathways, patient satisfaction, quality of life (QoL), and utilization of health care resources and the corresponding costs. The PREFER in VTE registry has been designed to address this and to understand medical care and needs as well as potential gaps for improvement. Methods/design: The PREFER in VTE registry was a prospective, observational, multicenter study conducted in seven European countries including Austria, France Germany, Italy, Spain, Switzerland, and the UK to assess the characteristics and the management of patients with VTE, the use of health care resources, and to provide data to estimate the costs for 12 months treatment following a first-time and/or recurrent VTE diagnosed in hospitals or specialized or primary care centers. In addition, existing anticoagulant treatment patterns, patient pathways, clinical outcomes, treatment satisfaction, and health related QoL were documented. The centers were chosen to reflect the care environment in which patients with VTE are managed in each of the participating countries. Patients were eligible to be enrolled into the registry if they were at least 18 years old, had a symptomatic, objectively confirmed first time or recurrent acute VTE defined as either distal or proximal deep vein thrombosis, pulmonary embolism or both. After the baseline visit at the time of the acute VTE event, further follow-up documentations occurred at 1, 3, 6 and 12 months. Follow-up data was collected by either routinely scheduled visits or by telephone calls. Results: Overall, 381 centers participated, which enrolled 3,545 patients during an observational period of 1 year. Conclusion: The PREFER in VTE registry will provide valuable insights into the characteristics of patients with VTE and their acute and mid-term management, as well as into drug utilization and the use of health care resources in acute first-time and/or recurrent VTE across Europe in clinical practice. Trial registration: Registered in DRKS register, ID number: DRKS00004795
| Original language | English |
|---|---|
| Article number | 41 |
| Journal | Thrombosis Journal |
| Volume | 13 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - Oct 21 2015 |
Keywords
- Anticoagulation
- Novel Oral Anticoagulants
- Prevention
- Registry
- Venous Thromboembolism
- Vitamin K antagonists
ASJC Scopus subject areas
- Hematology
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The management of acute venous thromboembolism in clinical practice - study rationale and protocol of the European PREFER in VTE Registry. / Agnelli, Giancarlo; Gitt, Anselm K.; Bauersachs, Rupert; Fronk, Eva Maria; Laeis, Petra; Mismetti, Patrick; Monreal, Manuel; Willich, Stefan N.; Wolf, Wolf Peter; Cohen, Alexander T.; Brodmann, Marianne; Rief, Peter; Eischer, Lisbeth; Stoshikj, Slagjana; Hirschl, Michael; Weinmann, Serge; Marschang, Peter; Abbadie, Fabrice; Achkar, Antoine; Addala, Azeddine; Adnet, Frédéric; Alexandra, Jean François; Aquilanti, Sandro; Belhassane, Abdelkader; Benaroya, Anne; Berremili, Toufek; Grenot, Marie Chevallier; Birr, Virginie; Holtea, Daniela; Bonnin, Christophe; Bosler, Frederic; Durand, Marie Gabrielle Bresin; Brisot, Dominique; Brousse, Christophe; De La Fuente, Tarodo; Cayman, Richard; Cazaubon, Michèle; Champion, Olivier; Chanut, Myriam; Chevalet, Pascal; Connault, Jerome; Durant, Cecile; Constans, Joel; Cordeanu, Mihaela; Couturaud, Francis; Lacut, Karine; De Dedker, Laure; Decoulx, Eric; Derrien, Benoit; Diamand, Jean Marc; Diard, Antoine; Douadi, Youssef; Dupas, Stephane; Remond, Santhi Samy Modeliar; Sevestre, Marie Antoinette; Edhery, Stéphane; Falvo, Nicolas; Taralunga, Claudia Farcas; Ferrari, Emile; Gaillard, Catherine; Garrigues, Damien; Gillet, Jean Luc; Giordana, Pascal; Grange, Claire; Vital-Durand, Denis; Grare, Frédérick; Henni, Amine Hadj; Heuser, Simone; Schmidt, Jeannot; Hidden-Henic, Valérie; Hottin, Delphine; Imbert, Bernard; Pernod, Gilles; Jakob, Daniel; Jacquinandi, Vincent; Jurus, Christine; Lacoste, Amelie; Laroche, Jean Pierre; Martin, Myriam; Mazollier, Cyrille; Mersel, Tahar; Miserey, Gilles; Nedey, Charles; Nou, Monica; Quere, Isabelle; Ouvry, Pierre; Peuch, Bernadette; Pichot, Olivier; Poulain, Veyre; Ray, Patrick; Rifai, Abed; Roy, Pierre Marie; Saby, Jean Claude; Simon, Frédéric; Simonot-Lalandec, Eliane; Stephan, Dominique; Tissot, Anne; Vodoungnon, Hubert; Adamczyk, Annette; Schnabl, Saskia; Ahmad, Wail Al; Weber, Heinz; Axthelm, Christoph; Bergmann, Klaus; Beschorner, Ulrich; Knittel, Matthias; Binias, Karl Heinz; Pasligh, Martin; Boral, Mehmet; Friederike, Girke; Bratsch, Hermann; Brauer, Gunter; Burghard, Sebastian; Demann, Christiane; Rennebaum, Carsten; Demmig, Anita; Eberlein, Ulrich; Enger, Frank; Eschenburg, Jens; Forkmann, Lutz; Frank, Jürgen; Freischmidt, Holger; Gassauer, Martin; Fritsche, Ilona; Kubicek-Hofmann, Cornelia; Goebels, Mark Claudius; Guggenbichler, Stephan; Härtel, Dirk; Hartmann, Karsten; Heilberger, Peter; Heinsius, Andreas; Held, Michael; Schnupp, Steffen; Herman, Georg; Herold, Jörg; Hertrich, Frank; Hommel, Henrike; Hütte, Guntram; Kalka, Christoph; Jungandreas, Katja; Ramthor, Mathias; Karcher, Jan; Werner, Nicolas; Karl-Wollweber, Susanne; Keilhau, Dag Alexander; Kittel, Kerstin; Knolinski, Tanja; Köhler, Christina; Werth, Sebastian; Kopplin, Ute; Körner, Ines; Wittig, Kathrin; Kröger, Knut; Moysidis, Theodoros; Kroschel, Ulf; Leschke, Matthias; zur Nieden, Tim; Lübbert, Gerhard; Lutz, Arno; Wucherpfennig, Petra; Marencke, Geert H.; Mortensen, Kai; Reppel, Michael; Nelles, Heike; Nestler, Kay; Neumeister, Axel; Schlosser, Alexander; Oettler, Wolfram; Ott, Ilka; Otto, Annegret; Pertermann, Astrid; Pfister, Rahel; Pindur, Lukas; Pourhassan, Siamak; Predel, Diethard; Pudollek, Thomas; Reimer, Dietrich; Richter, Cornelia; Rieker, Eberhad; Rothenbücher, Gabriele; Rothhagen, Brigitte; Rudolff, Simone; Stücker, Markus; Schäfer, Andreas; Sonnenschein, Kristina; Schafnitzl, Wolfgang; Schellong, Sebastian; Voigts, Birgit; Schiller, Martin; Schmeink, Thomas; Schneider, Henrik; Schön, Norbert; Schulze, Matthias; Sechtem, Udo; Sedl, Sabine; Werno, Harriet Simone; Stachowitz, Jörg; Thieme, Marcus; Tiefenbacher, Christiane; Tsantilas, Dimitrios; Vieth, Petra; vom Dahl, Jürgen; Grün-Himmelmann, Katharina; von Bilderling, Peter; von Maltik, Thordis; Weinrich, Katrin; Weyer, Marc; Köln, Eduardus Krankenhaus; Wirtz, Peter; Wittig, Ina; Zierock, Petra; Ageno, Walter; Caprioli, Monica; Rancan, Elena; Guercini, Francesco; Mommi, Valeria; Amitrano, Maria; Cannavacciuolo, Francesca; Amore, Maurizio; D'Antoni, Sebastiano; Angelini, Ermanno; Forgia, Saverio La; Antignani, Pier Luigi; Calandra, Giuseppe; Arone, Andrea; Perticone, Francesco; Sciacqua, Angela; Asaro, Giovanni; Bellisi, Mario; Attanzio, Maria Teresa; Pinto, Antonio; Attinasi, Valerio; Cillari, Enrico; Sorvillo, Sabrina; Balbarini, Alberto; Santini, Claudia; Violo, Caterina; Banfi, Elena; Lodigiani, Corrado; Barcellona, Doris; Delpin, Stefano; Marongiu, Silvia; Barillari, Giovanni; Pasca, Samantha; Bartolini, Claudia; Verdecchia, Paolo; Bartone, Mosè; Mancuso, Gerardo; Bellanuova, Ignazio; Felis, Salvatore; Bellizzi, Annamaria; Masotti, Luca; Bianchi, Marina; Carugati, Anna; Bianchini, Giuseppe; Guarnera, Giorgio; Boari, Benedetta; Gallerani, Massimo; Pasin, Mauro; Bortoluzzi, Cristiano; Parisi, Roberto; Brucoli, Caterina; Palasciano, Giuseppe; Camporese, Giuseppe; Tonello, Chiara; Canafoglia, Lucia; Rupoli, Serena; Cancellieri, Emilia; Paoletti, Oriana; Testa, Sophie; Carlizza, Anita; Carnovali, Marino; Sada, Simona; Samaden, Anna; Casarsa, Chiara; Mearelli, Filippo; Pivetti, Giulia; Catalini, Roberto; Zingaretti, Oriana; Vascolare, Medicina; Cavazza, Stefania; Cosmi, Benilde; Cenci, Caterina; Prisco, Domenico; Silvestri, Elena; Ceresa, Fabrizio; Patanè, Francesco; Ciampa, Antonio; Siniscalchi, Valeria; Ciarambino, Tiziana; De Bartolomeo, Giuseppe; Clemente, Michele; Conti, Franco; Paiella, Laura; D'Avino, Maria; D'Alessandro, Aldo; Placentino, Marisa; Sollazzo, Vito; D'Angelo, Armando; Viganò, Silvana; De Campora, Paolo; Sangiuolo, Raffaele; De Franciscis, Stefano; Serra, Raffaele; De Gaudenzi, Egidio; De Santis, Fernando; Piccinni, Giovanni Carlo; De Tommaso, Italo D.; Di Francesco, Letizia; Vincentelli, Giovanni Maria; Di Maggio, Rosario; Saccullo, Giorgia; Siragusa, Sergio; Di Micco, Pierpaolo; Fontanella, Andrea; Di Michele, Dario; Di Minno, Giovanni; Tufano, Antonella; Di Nisio, Marcello; Porreca, Ettore; Donadio, Francesca; Imberti, Davide; Enea, Iolanda; Fabbian, Fabio; Manfredini, Roberto; Pala, Marco; Falanga, Anna; Milesi, Viola; Fiore, Valerio; Franco, Elio; Giudice, Giorgio; Frausini, Gabriele; Rovinelli, Marina; Fuorlo, Mariella; Landolfi, Raffaele; Morretti, Tiziana; Gamberini, Susanna; Salmi, Raffaella; Ghirarduzzi, Angelo; Veropalumbo, Maria Rosaria; Ghizzi, Mauro; Pepe, Carlo; Gianniello, Francesca; Martinelli, Ida; Iosub, Diana Irina; Piovella, Franco; Iozzi, Ercole; Talerico, Agostino; Regina, Micaela La; Orlandini, Francesco; Marconi, Letizia; Palla, Antonio; Marcucci, Rossella; Poli, Daniela; Margheriti, Riccardo; Sala, Gianpaolo; Marra, Alfonso; Marrocco, Fausto; Montagna, Elisabetta Sara; Silvestris, Franco; Vallarelli, Simona; Mos, Lucio; Rossetto, Valeria; Mugno, Francesco; Di Salvo, Michelangelo; Nitti, Cinzia; Pennacchioni, Milena; Salvi, Aldo; Olivieri, Oliviero; Tosi, Federica; Zorzi, Francesco; Onesta, Maicol; Pagliara, Valeria; Villalta, Sabina; Paolucci, Giancarlo; Severino, Salvatore; Pierri, Francesca; Russo, Vitantonio; Pizzini, Attilia Maria; Quintavalla, Roberto; Rubino, Pasquale; Ria, Luigi; Schenone, Alessandro; Strafino, Cosimo; Tropeano, Pietro; Vetrano, Alfredo; Zanatta, Nello; Cansino, Maria Dolores Adarraga; Gutierrez, Juan Alonso; de las Revillas, Francisco Arnaiz; Fernández, Cristina Amado; Mijares, Núria Calvo; Blanco-Molina, Maria Ángeles; Garcia, Maria Angelina; Seijo, Dolores Joya; Blazquez, Rocío Aranda; López-Sáez, Juan Bosco; Rodrigo, Eduardo Arellano; Blanch, Jaume Villalta; Arxe, Arola Armengou; Dalmau, Fernando García Bragado; Quincoces, Aitor Ballaz; Loizaga, Amaia García; Pérez, José Luis Beato; Díaz, Pedro Bedate; Loaiza, Andrés Quezada; Castellote, Marc Cairols; Alcántara, Inma Cañas; Padierna, Meritxell Lluís; Expósito, Marina Carrasco; Mas, Amparo Carrasco; Castro, Fernando Cereto; Sanz, Rafael Castrodeza; de Saracho, Juan Ortiz; de la Fuente, Elena Cisneros; de Ancos Aracil, Cristina; Ruiz, Justo Ruiz; de Daborenea González, Maria Dolores; Iglesias, Alfonso Fernández; de la Fuente Aguado, Javier; González, Lucia González; del Carmen Fernández-Capitán, Maria; Hernández, Alicia Lorenzo; del Toro Cervera, Jorge; Rus, Gloria Pérez; Bregel, Juan Luis Delgado; Fernández, Florentino Díez; Teresa Elias Hernández, Elias Hernández; Palomares, Luis Jara; Bataler, Ramón Ferri; Rodríguez, José Antonio Nieto; García, José María García; Porras, José Ramón González; García, María Guil; López, Elena Hernando; Lázaro, Alejandra Roncero; Jaras, María Jesús; Castro, David Jiménez; Madridejos, Rafael Jiménez Rodríguez; Navas, José María Pedrajas; Lecumberri, Ramón; Martínez, Nicolás; Castellanos, Genoveva Teresa López; Espinosa, Luis Manzano; Jiménez, Luciano López; Cobo, Olga Madridano; Saiz, Carmen Mainez; Pizarro, Yolanda Romero; Yglesias, Pablo Javier Marchena; Martín del Pozo, Mar; Melibovsky, Leonardo; Altarriba, Emilia Solé; Bosch, Manuel Monreal; Secades, Rafael Monte; Luján, José Maria Mora; Mestre, Antoni Riera; Moral, Pedro Moral; Parra, José Antonio Todolí; Flores, Aurora Moreno; Muñoz-Torrero, Juan Francisco Sánchez; Rodríguez, Francisco José Muñoz; Fernández, Manuel J Núñez; Sibajas, Estefanía Oncala; de Sedas, Mercedes Vaquero; Caballero, Pedro Parra; del Campo, Isaac Pons Martín; Sánchez, José Portillo; Gallego, Alberto Rivera; álvarez, Iria Villaverde; Beltrán, Eva Maria Rodríguez; Fuentes, Demetrio Sánchez; Schilling, Vanessa Roldán; álvarez, Julio Sánchez; López, Gregorio Tiberio; Caralt, José Maria Suriñach; Miranda, Raimundo Tirado; de Antonio, Esther Usandizaga; Banyai, Martin; Frank, Ulrich; Gian Reto Jörg, Reto Jörg; Jeanneret, Christina; Staub, Daniel; Ackroyd, Sam; Agarwal, Gaurav; Mearns, Ben; Alikhan, Raza; Allameddine, Allameddine; Al-Refaie, Faris; Arden, Christopher; Austin, Antony; Bakhai, Ameet; Barton, Thomas; Ewad, Hayder; Body, Richard; Thachil, Jecko; Chacko, Joseph; Chandra, Deepak; Charters, Freda; Church, Alistair; McGrane, Frances; Clements, John; Clifford, Piers; Cox, Dominic; Crouch, Matthew; Crowther, Mark; Davies, Emyr; Davies, Mark; Dimitri, Sameh; Drebes, Anja; Franklin, Simon; George, Jacob; Irvine, Nicola; Gerofke, Hagen; Gibbs, Christopher; Goh, Teik; Gupta, Sunil; Holmes, Jon; Jackson-Voyzey, Ewart; Jones, Nick; Kallat, Arun; Kerr, Patrick; Kesteven, Patrick; Lench, Tristan; Lester, William; Lowe, Gillian; Lewis, Martin; McCormack, Terry; McCoye, Andrew; Moriarty, Andrew; Morris, Wendy; Myers, Bethan; Narayanan, Mekkali; Oo, New; Reed, Matthew; Rose, Peter; Saja, Khalid; Sivakumaran, Muttuswamy; Sohal, Mamta; Solomons, Gary; Sultanzadeh, Sayed J.; Venton, Tamsin; Wakeling, John; Walby, Ceri; Waldron, Michael; Watt, Simon; Willcock, William; Zafar, Azhar.
In: Thrombosis Journal, Vol. 13, No. 1, 41, 21.10.2015.Research output: Contribution to journal › Article › peer-review
}
TY - JOUR
T1 - The management of acute venous thromboembolism in clinical practice - study rationale and protocol of the European PREFER in VTE Registry
AU - Agnelli, Giancarlo
AU - Gitt, Anselm K.
AU - Bauersachs, Rupert
AU - Fronk, Eva Maria
AU - Laeis, Petra
AU - Mismetti, Patrick
AU - Monreal, Manuel
AU - Willich, Stefan N.
AU - Wolf, Wolf Peter
AU - Cohen, Alexander T.
AU - Brodmann, Marianne
AU - Rief, Peter
AU - Eischer, Lisbeth
AU - Stoshikj, Slagjana
AU - Hirschl, Michael
AU - Weinmann, Serge
AU - Marschang, Peter
AU - Abbadie, Fabrice
AU - Achkar, Antoine
AU - Addala, Azeddine
AU - Adnet, Frédéric
AU - Alexandra, Jean François
AU - Aquilanti, Sandro
AU - Belhassane, Abdelkader
AU - Benaroya, Anne
AU - Berremili, Toufek
AU - Grenot, Marie Chevallier
AU - Birr, Virginie
AU - Holtea, Daniela
AU - Bonnin, Christophe
AU - Bosler, Frederic
AU - Durand, Marie Gabrielle Bresin
AU - Brisot, Dominique
AU - Brousse, Christophe
AU - De La Fuente, Tarodo
AU - Cayman, Richard
AU - Cazaubon, Michèle
AU - Champion, Olivier
AU - Chanut, Myriam
AU - Chevalet, Pascal
AU - Connault, Jerome
AU - Durant, Cecile
AU - Constans, Joel
AU - Cordeanu, Mihaela
AU - Couturaud, Francis
AU - Lacut, Karine
AU - De Dedker, Laure
AU - Decoulx, Eric
AU - Derrien, Benoit
AU - Diamand, Jean Marc
AU - Diard, Antoine
AU - Douadi, Youssef
AU - Dupas, Stephane
AU - Remond, Santhi Samy Modeliar
AU - Sevestre, Marie Antoinette
AU - Edhery, Stéphane
AU - Falvo, Nicolas
AU - Taralunga, Claudia Farcas
AU - Ferrari, Emile
AU - Gaillard, Catherine
AU - Garrigues, Damien
AU - Gillet, Jean Luc
AU - Giordana, Pascal
AU - Grange, Claire
AU - Vital-Durand, Denis
AU - Grare, Frédérick
AU - Henni, Amine Hadj
AU - Heuser, Simone
AU - Schmidt, Jeannot
AU - Hidden-Henic, Valérie
AU - Hottin, Delphine
AU - Imbert, Bernard
AU - Pernod, Gilles
AU - Jakob, Daniel
AU - Jacquinandi, Vincent
AU - Jurus, Christine
AU - Lacoste, Amelie
AU - Laroche, Jean Pierre
AU - Martin, Myriam
AU - Mazollier, Cyrille
AU - Mersel, Tahar
AU - Miserey, Gilles
AU - Nedey, Charles
AU - Nou, Monica
AU - Quere, Isabelle
AU - Ouvry, Pierre
AU - Peuch, Bernadette
AU - Pichot, Olivier
AU - Poulain, Veyre
AU - Ray, Patrick
AU - Rifai, Abed
AU - Roy, Pierre Marie
AU - Saby, Jean Claude
AU - Simon, Frédéric
AU - Simonot-Lalandec, Eliane
AU - Stephan, Dominique
AU - Tissot, Anne
AU - Vodoungnon, Hubert
AU - Adamczyk, Annette
AU - Schnabl, Saskia
AU - Ahmad, Wail Al
AU - Weber, Heinz
AU - Axthelm, Christoph
AU - Bergmann, Klaus
AU - Beschorner, Ulrich
AU - Knittel, Matthias
AU - Binias, Karl Heinz
AU - Pasligh, Martin
AU - Boral, Mehmet
AU - Friederike, Girke
AU - Bratsch, Hermann
AU - Brauer, Gunter
AU - Burghard, Sebastian
AU - Demann, Christiane
AU - Rennebaum, Carsten
AU - Demmig, Anita
AU - Eberlein, Ulrich
AU - Enger, Frank
AU - Eschenburg, Jens
AU - Forkmann, Lutz
AU - Frank, Jürgen
AU - Freischmidt, Holger
AU - Gassauer, Martin
AU - Fritsche, Ilona
AU - Kubicek-Hofmann, Cornelia
AU - Goebels, Mark Claudius
AU - Guggenbichler, Stephan
AU - Härtel, Dirk
AU - Hartmann, Karsten
AU - Heilberger, Peter
AU - Heinsius, Andreas
AU - Held, Michael
AU - Schnupp, Steffen
AU - Herman, Georg
AU - Herold, Jörg
AU - Hertrich, Frank
AU - Hommel, Henrike
AU - Hütte, Guntram
AU - Kalka, Christoph
AU - Jungandreas, Katja
AU - Ramthor, Mathias
AU - Karcher, Jan
AU - Werner, Nicolas
AU - Karl-Wollweber, Susanne
AU - Keilhau, Dag Alexander
AU - Kittel, Kerstin
AU - Knolinski, Tanja
AU - Köhler, Christina
AU - Werth, Sebastian
AU - Kopplin, Ute
AU - Körner, Ines
AU - Wittig, Kathrin
AU - Kröger, Knut
AU - Moysidis, Theodoros
AU - Kroschel, Ulf
AU - Leschke, Matthias
AU - zur Nieden, Tim
AU - Lübbert, Gerhard
AU - Lutz, Arno
AU - Wucherpfennig, Petra
AU - Marencke, Geert H.
AU - Mortensen, Kai
AU - Reppel, Michael
AU - Nelles, Heike
AU - Nestler, Kay
AU - Neumeister, Axel
AU - Schlosser, Alexander
AU - Oettler, Wolfram
AU - Ott, Ilka
AU - Otto, Annegret
AU - Pertermann, Astrid
AU - Pfister, Rahel
AU - Pindur, Lukas
AU - Pourhassan, Siamak
AU - Predel, Diethard
AU - Pudollek, Thomas
AU - Reimer, Dietrich
AU - Richter, Cornelia
AU - Rieker, Eberhad
AU - Rothenbücher, Gabriele
AU - Rothhagen, Brigitte
AU - Rudolff, Simone
AU - Stücker, Markus
AU - Schäfer, Andreas
AU - Sonnenschein, Kristina
AU - Schafnitzl, Wolfgang
AU - Schellong, Sebastian
AU - Voigts, Birgit
AU - Schiller, Martin
AU - Schmeink, Thomas
AU - Schneider, Henrik
AU - Schön, Norbert
AU - Schulze, Matthias
AU - Sechtem, Udo
AU - Sedl, Sabine
AU - Werno, Harriet Simone
AU - Stachowitz, Jörg
AU - Thieme, Marcus
AU - Tiefenbacher, Christiane
AU - Tsantilas, Dimitrios
AU - Vieth, Petra
AU - vom Dahl, Jürgen
AU - Grün-Himmelmann, Katharina
AU - von Bilderling, Peter
AU - von Maltik, Thordis
AU - Weinrich, Katrin
AU - Weyer, Marc
AU - Köln, Eduardus Krankenhaus
AU - Wirtz, Peter
AU - Wittig, Ina
AU - Zierock, Petra
AU - Ageno, Walter
AU - Caprioli, Monica
AU - Rancan, Elena
AU - Guercini, Francesco
AU - Mommi, Valeria
AU - Amitrano, Maria
AU - Cannavacciuolo, Francesca
AU - Amore, Maurizio
AU - D'Antoni, Sebastiano
AU - Angelini, Ermanno
AU - Forgia, Saverio La
AU - Antignani, Pier Luigi
AU - Calandra, Giuseppe
AU - Arone, Andrea
AU - Perticone, Francesco
AU - Sciacqua, Angela
AU - Asaro, Giovanni
AU - Bellisi, Mario
AU - Attanzio, Maria Teresa
AU - Pinto, Antonio
AU - Attinasi, Valerio
AU - Cillari, Enrico
AU - Sorvillo, Sabrina
AU - Balbarini, Alberto
AU - Santini, Claudia
AU - Violo, Caterina
AU - Banfi, Elena
AU - Lodigiani, Corrado
AU - Barcellona, Doris
AU - Delpin, Stefano
AU - Marongiu, Silvia
AU - Barillari, Giovanni
AU - Pasca, Samantha
AU - Bartolini, Claudia
AU - Verdecchia, Paolo
AU - Bartone, Mosè
AU - Mancuso, Gerardo
AU - Bellanuova, Ignazio
AU - Felis, Salvatore
AU - Bellizzi, Annamaria
AU - Masotti, Luca
AU - Bianchi, Marina
AU - Carugati, Anna
AU - Bianchini, Giuseppe
AU - Guarnera, Giorgio
AU - Boari, Benedetta
AU - Gallerani, Massimo
AU - Pasin, Mauro
AU - Bortoluzzi, Cristiano
AU - Parisi, Roberto
AU - Brucoli, Caterina
AU - Palasciano, Giuseppe
AU - Camporese, Giuseppe
AU - Tonello, Chiara
AU - Canafoglia, Lucia
AU - Rupoli, Serena
AU - Cancellieri, Emilia
AU - Paoletti, Oriana
AU - Testa, Sophie
AU - Carlizza, Anita
AU - Carnovali, Marino
AU - Sada, Simona
AU - Samaden, Anna
AU - Casarsa, Chiara
AU - Mearelli, Filippo
AU - Pivetti, Giulia
AU - Catalini, Roberto
AU - Zingaretti, Oriana
AU - Vascolare, Medicina
AU - Cavazza, Stefania
AU - Cosmi, Benilde
AU - Cenci, Caterina
AU - Prisco, Domenico
AU - Silvestri, Elena
AU - Ceresa, Fabrizio
AU - Patanè, Francesco
AU - Ciampa, Antonio
AU - Siniscalchi, Valeria
AU - Ciarambino, Tiziana
AU - De Bartolomeo, Giuseppe
AU - Clemente, Michele
AU - Conti, Franco
AU - Paiella, Laura
AU - D'Avino, Maria
AU - D'Alessandro, Aldo
AU - Placentino, Marisa
AU - Sollazzo, Vito
AU - D'Angelo, Armando
AU - Viganò, Silvana
AU - De Campora, Paolo
AU - Sangiuolo, Raffaele
AU - De Franciscis, Stefano
AU - Serra, Raffaele
AU - De Gaudenzi, Egidio
AU - De Santis, Fernando
AU - Piccinni, Giovanni Carlo
AU - De Tommaso, Italo D.
AU - Di Francesco, Letizia
AU - Vincentelli, Giovanni Maria
AU - Di Maggio, Rosario
AU - Saccullo, Giorgia
AU - Siragusa, Sergio
AU - Di Micco, Pierpaolo
AU - Fontanella, Andrea
AU - Di Michele, Dario
AU - Di Minno, Giovanni
AU - Tufano, Antonella
AU - Di Nisio, Marcello
AU - Porreca, Ettore
AU - Donadio, Francesca
AU - Imberti, Davide
AU - Enea, Iolanda
AU - Fabbian, Fabio
AU - Manfredini, Roberto
AU - Pala, Marco
AU - Falanga, Anna
AU - Milesi, Viola
AU - Fiore, Valerio
AU - Franco, Elio
AU - Giudice, Giorgio
AU - Frausini, Gabriele
AU - Rovinelli, Marina
AU - Fuorlo, Mariella
AU - Landolfi, Raffaele
AU - Morretti, Tiziana
AU - Gamberini, Susanna
AU - Salmi, Raffaella
AU - Ghirarduzzi, Angelo
AU - Veropalumbo, Maria Rosaria
AU - Ghizzi, Mauro
AU - Pepe, Carlo
AU - Gianniello, Francesca
AU - Martinelli, Ida
AU - Iosub, Diana Irina
AU - Piovella, Franco
AU - Iozzi, Ercole
AU - Talerico, Agostino
AU - Regina, Micaela La
AU - Orlandini, Francesco
AU - Marconi, Letizia
AU - Palla, Antonio
AU - Marcucci, Rossella
AU - Poli, Daniela
AU - Margheriti, Riccardo
AU - Sala, Gianpaolo
AU - Marra, Alfonso
AU - Marrocco, Fausto
AU - Montagna, Elisabetta Sara
AU - Silvestris, Franco
AU - Vallarelli, Simona
AU - Mos, Lucio
AU - Rossetto, Valeria
AU - Mugno, Francesco
AU - Di Salvo, Michelangelo
AU - Nitti, Cinzia
AU - Pennacchioni, Milena
AU - Salvi, Aldo
AU - Olivieri, Oliviero
AU - Tosi, Federica
AU - Zorzi, Francesco
AU - Onesta, Maicol
AU - Pagliara, Valeria
AU - Villalta, Sabina
AU - Paolucci, Giancarlo
AU - Severino, Salvatore
AU - Pierri, Francesca
AU - Russo, Vitantonio
AU - Pizzini, Attilia Maria
AU - Quintavalla, Roberto
AU - Rubino, Pasquale
AU - Ria, Luigi
AU - Schenone, Alessandro
AU - Strafino, Cosimo
AU - Tropeano, Pietro
AU - Vetrano, Alfredo
AU - Zanatta, Nello
AU - Cansino, Maria Dolores Adarraga
AU - Gutierrez, Juan Alonso
AU - de las Revillas, Francisco Arnaiz
AU - Fernández, Cristina Amado
AU - Mijares, Núria Calvo
AU - Blanco-Molina, Maria Ángeles
AU - Garcia, Maria Angelina
AU - Seijo, Dolores Joya
AU - Blazquez, Rocío Aranda
AU - López-Sáez, Juan Bosco
AU - Rodrigo, Eduardo Arellano
AU - Blanch, Jaume Villalta
AU - Arxe, Arola Armengou
AU - Dalmau, Fernando García Bragado
AU - Quincoces, Aitor Ballaz
AU - Loizaga, Amaia García
AU - Pérez, José Luis Beato
AU - Díaz, Pedro Bedate
AU - Loaiza, Andrés Quezada
AU - Castellote, Marc Cairols
AU - Alcántara, Inma Cañas
AU - Padierna, Meritxell Lluís
AU - Expósito, Marina Carrasco
AU - Mas, Amparo Carrasco
AU - Castro, Fernando Cereto
AU - Sanz, Rafael Castrodeza
AU - de Saracho, Juan Ortiz
AU - de la Fuente, Elena Cisneros
AU - de Ancos Aracil, Cristina
AU - Ruiz, Justo Ruiz
AU - de Daborenea González, Maria Dolores
AU - Iglesias, Alfonso Fernández
AU - de la Fuente Aguado, Javier
AU - González, Lucia González
AU - del Carmen Fernández-Capitán, Maria
AU - Hernández, Alicia Lorenzo
AU - del Toro Cervera, Jorge
AU - Rus, Gloria Pérez
AU - Bregel, Juan Luis Delgado
AU - Fernández, Florentino Díez
AU - Teresa Elias Hernández, Elias Hernández
AU - Palomares, Luis Jara
AU - Bataler, Ramón Ferri
AU - Rodríguez, José Antonio Nieto
AU - García, José María García
AU - Porras, José Ramón González
AU - García, María Guil
AU - López, Elena Hernando
AU - Lázaro, Alejandra Roncero
AU - Jaras, María Jesús
AU - Castro, David Jiménez
AU - Madridejos, Rafael Jiménez Rodríguez
AU - Navas, José María Pedrajas
AU - Lecumberri, Ramón
AU - Martínez, Nicolás
AU - Castellanos, Genoveva Teresa López
AU - Espinosa, Luis Manzano
AU - Jiménez, Luciano López
AU - Cobo, Olga Madridano
AU - Saiz, Carmen Mainez
AU - Pizarro, Yolanda Romero
AU - Yglesias, Pablo Javier Marchena
AU - Martín del Pozo, Mar
AU - Melibovsky, Leonardo
AU - Altarriba, Emilia Solé
AU - Bosch, Manuel Monreal
AU - Secades, Rafael Monte
AU - Luján, José Maria Mora
AU - Mestre, Antoni Riera
AU - Moral, Pedro Moral
AU - Parra, José Antonio Todolí
AU - Flores, Aurora Moreno
AU - Muñoz-Torrero, Juan Francisco Sánchez
AU - Rodríguez, Francisco José Muñoz
AU - Fernández, Manuel J Núñez
AU - Sibajas, Estefanía Oncala
AU - de Sedas, Mercedes Vaquero
AU - Caballero, Pedro Parra
AU - del Campo, Isaac Pons Martín
AU - Sánchez, José Portillo
AU - Gallego, Alberto Rivera
AU - álvarez, Iria Villaverde
AU - Beltrán, Eva Maria Rodríguez
AU - Fuentes, Demetrio Sánchez
AU - Schilling, Vanessa Roldán
AU - álvarez, Julio Sánchez
AU - López, Gregorio Tiberio
AU - Caralt, José Maria Suriñach
AU - Miranda, Raimundo Tirado
AU - de Antonio, Esther Usandizaga
AU - Banyai, Martin
AU - Frank, Ulrich
AU - Gian Reto Jörg, Reto Jörg
AU - Jeanneret, Christina
AU - Staub, Daniel
AU - Ackroyd, Sam
AU - Agarwal, Gaurav
AU - Mearns, Ben
AU - Alikhan, Raza
AU - Allameddine, Allameddine
AU - Al-Refaie, Faris
AU - Arden, Christopher
AU - Austin, Antony
AU - Bakhai, Ameet
AU - Barton, Thomas
AU - Ewad, Hayder
AU - Body, Richard
AU - Thachil, Jecko
AU - Chacko, Joseph
AU - Chandra, Deepak
AU - Charters, Freda
AU - Church, Alistair
AU - McGrane, Frances
AU - Clements, John
AU - Clifford, Piers
AU - Cox, Dominic
AU - Crouch, Matthew
AU - Crowther, Mark
AU - Davies, Emyr
AU - Davies, Mark
AU - Dimitri, Sameh
AU - Drebes, Anja
AU - Franklin, Simon
AU - George, Jacob
AU - Irvine, Nicola
AU - Gerofke, Hagen
AU - Gibbs, Christopher
AU - Goh, Teik
AU - Gupta, Sunil
AU - Holmes, Jon
AU - Jackson-Voyzey, Ewart
AU - Jones, Nick
AU - Kallat, Arun
AU - Kerr, Patrick
AU - Kesteven, Patrick
AU - Lench, Tristan
AU - Lester, William
AU - Lowe, Gillian
AU - Lewis, Martin
AU - McCormack, Terry
AU - McCoye, Andrew
AU - Moriarty, Andrew
AU - Morris, Wendy
AU - Myers, Bethan
AU - Narayanan, Mekkali
AU - Oo, New
AU - Reed, Matthew
AU - Rose, Peter
AU - Saja, Khalid
AU - Sivakumaran, Muttuswamy
AU - Sohal, Mamta
AU - Solomons, Gary
AU - Sultanzadeh, Sayed J.
AU - Venton, Tamsin
AU - Wakeling, John
AU - Walby, Ceri
AU - Waldron, Michael
AU - Watt, Simon
AU - Willcock, William
AU - Zafar, Azhar
PY - 2015/10/21
Y1 - 2015/10/21
N2 - Background: Venous thromboembolism (VTE) is a major health problem, with over one million events every year in Europe. However, there is a paucity of data on the current management in real life, including factors influencing treatment pathways, patient satisfaction, quality of life (QoL), and utilization of health care resources and the corresponding costs. The PREFER in VTE registry has been designed to address this and to understand medical care and needs as well as potential gaps for improvement. Methods/design: The PREFER in VTE registry was a prospective, observational, multicenter study conducted in seven European countries including Austria, France Germany, Italy, Spain, Switzerland, and the UK to assess the characteristics and the management of patients with VTE, the use of health care resources, and to provide data to estimate the costs for 12 months treatment following a first-time and/or recurrent VTE diagnosed in hospitals or specialized or primary care centers. In addition, existing anticoagulant treatment patterns, patient pathways, clinical outcomes, treatment satisfaction, and health related QoL were documented. The centers were chosen to reflect the care environment in which patients with VTE are managed in each of the participating countries. Patients were eligible to be enrolled into the registry if they were at least 18 years old, had a symptomatic, objectively confirmed first time or recurrent acute VTE defined as either distal or proximal deep vein thrombosis, pulmonary embolism or both. After the baseline visit at the time of the acute VTE event, further follow-up documentations occurred at 1, 3, 6 and 12 months. Follow-up data was collected by either routinely scheduled visits or by telephone calls. Results: Overall, 381 centers participated, which enrolled 3,545 patients during an observational period of 1 year. Conclusion: The PREFER in VTE registry will provide valuable insights into the characteristics of patients with VTE and their acute and mid-term management, as well as into drug utilization and the use of health care resources in acute first-time and/or recurrent VTE across Europe in clinical practice. Trial registration: Registered in DRKS register, ID number: DRKS00004795
AB - Background: Venous thromboembolism (VTE) is a major health problem, with over one million events every year in Europe. However, there is a paucity of data on the current management in real life, including factors influencing treatment pathways, patient satisfaction, quality of life (QoL), and utilization of health care resources and the corresponding costs. The PREFER in VTE registry has been designed to address this and to understand medical care and needs as well as potential gaps for improvement. Methods/design: The PREFER in VTE registry was a prospective, observational, multicenter study conducted in seven European countries including Austria, France Germany, Italy, Spain, Switzerland, and the UK to assess the characteristics and the management of patients with VTE, the use of health care resources, and to provide data to estimate the costs for 12 months treatment following a first-time and/or recurrent VTE diagnosed in hospitals or specialized or primary care centers. In addition, existing anticoagulant treatment patterns, patient pathways, clinical outcomes, treatment satisfaction, and health related QoL were documented. The centers were chosen to reflect the care environment in which patients with VTE are managed in each of the participating countries. Patients were eligible to be enrolled into the registry if they were at least 18 years old, had a symptomatic, objectively confirmed first time or recurrent acute VTE defined as either distal or proximal deep vein thrombosis, pulmonary embolism or both. After the baseline visit at the time of the acute VTE event, further follow-up documentations occurred at 1, 3, 6 and 12 months. Follow-up data was collected by either routinely scheduled visits or by telephone calls. Results: Overall, 381 centers participated, which enrolled 3,545 patients during an observational period of 1 year. Conclusion: The PREFER in VTE registry will provide valuable insights into the characteristics of patients with VTE and their acute and mid-term management, as well as into drug utilization and the use of health care resources in acute first-time and/or recurrent VTE across Europe in clinical practice. Trial registration: Registered in DRKS register, ID number: DRKS00004795
KW - Anticoagulation
KW - Novel Oral Anticoagulants
KW - Prevention
KW - Registry
KW - Venous Thromboembolism
KW - Vitamin K antagonists
UR - http://www.scopus.com/inward/record.url?scp=84944896576&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84944896576&partnerID=8YFLogxK
U2 - 10.1186/s12959-015-0071-z
DO - 10.1186/s12959-015-0071-z
M3 - Article
AN - SCOPUS:84944896576
VL - 13
JO - Thrombosis Journal
JF - Thrombosis Journal
SN - 1477-9560
IS - 1
M1 - 41
ER -