The management of soft tissue tumours of the abdominal wall

H. G. Smith, D. Tzanis, C. Messiou, C. Benson, J. A. van der Hage, M. Fiore, S. Bonvalot, A. J. Hayes

Research output: Contribution to journalReview articlepeer-review

Abstract

Background Soft tissue tumours of the abdominal wall account for approximately 10% of all soft tissue tumours. Tumours at this site comprise a heterogeneous group of pathologies with distinct clinical behaviours and responses to treatment. The management of these tumours has largely been extrapolated from studies of soft tissue tumours at other sites. This review aims to summarise the existing data relating to abdominal wall tumours and suggest principles for managing soft tissue tumours at this site. Methods Relevant articles were retrieved from a comprehensive literature search using the PubMed database. Key words included abdominal wall, soft tissue tumours, surgery, radiotherapy and chemotherapy. No restrictions on publication date were used. Results The most common pathologies presenting in the abdominal wall are desmoid tumours, soft-tissue sarcoma and dermatofibrosarcoma protuberans (DFSP). Desmoid tumours should be managed with an initial period of observation, with surgery reserved for progressive lesions. Surgery should be the primary treatment for soft-tissue sarcomas and DFSP, with radiotherapy reserved for large-high grade tumours and preferentially given pre-operatively. Conclusions Abdominal wall tumours are rare and should be managed in centres with experience in the management of soft tissue tumours. Management should be tailored to the biological behaviour of specific pathologies.

Original languageEnglish
Pages (from-to)1647-1655
Number of pages9
JournalEuropean Journal of Surgical Oncology
Volume43
Issue number9
DOIs
Publication statusPublished - Sep 1 2017

Keywords

  • Abdominal wall
  • Dermatofibrosarcoma protuberans
  • Desmoid tumours
  • Soft tissue sarcoma

ASJC Scopus subject areas

  • Surgery
  • Oncology

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