The many roles of an RNA editor

Liam P. Keegan, Angela Gallo, Mary A. O'Connell

Research output: Contribution to journalArticle

181 Citations (Scopus)

Abstract

The availability of complete genome sequences has made it clear that gene number is not the sole determinant of the complexity of the proteome. Additional complexity that is not readily detected by genome analysis is present in the number and types of RNA transcript that can be derived from each locus. Although alternative splicing is a well-recognized method of generating diversity, the more subtle mechanism of RNA editing is less familiar. MRC Human Genetics.

Original languageEnglish
Pages (from-to)869-878
Number of pages10
JournalNature Reviews Genetics
Volume2
Issue number11
DOIs
Publication statusPublished - Nov 2001

Fingerprint

Genome
RNA
RNA Editing
RNA editing
genome
alternative splicing
Medical Genetics
Alternative Splicing
Proteome
messenger RNA
proteome
loci
Genes
genes
methodology

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Genetics
  • Genetics(clinical)

Cite this

The many roles of an RNA editor. / Keegan, Liam P.; Gallo, Angela; O'Connell, Mary A.

In: Nature Reviews Genetics, Vol. 2, No. 11, 11.2001, p. 869-878.

Research output: Contribution to journalArticle

Keegan, LP, Gallo, A & O'Connell, MA 2001, 'The many roles of an RNA editor', Nature Reviews Genetics, vol. 2, no. 11, pp. 869-878. https://doi.org/10.1038/35098584
Keegan, Liam P. ; Gallo, Angela ; O'Connell, Mary A. / The many roles of an RNA editor. In: Nature Reviews Genetics. 2001 ; Vol. 2, No. 11. pp. 869-878.
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