The MET receptor tyrosine kinase in invasion and metastasis

Silvia Benvenuti, Paolo M. Comoglio

Research output: Contribution to journalArticle

Abstract

Various cytokines and soluble growth factors upon interaction with their membrane receptors are responsible for inducing cellular proliferation, differentiation, movement, and protection from anoikis (a planned suicide activated by normal cells in absence of attachment to neighboring cells or extracellular matrix (EMC)). Among those soluble factors a major position is exerted by hepatocyte growth factor (HGF) together with its receptor MET and macrophage-stimulating protein (MSP) in cooperation with its receptor RON.

Original languageEnglish
Pages (from-to)316-325
Number of pages10
JournalJournal of Cellular Physiology
Volume213
Issue number2
DOIs
Publication statusPublished - Nov 2007

ASJC Scopus subject areas

  • Clinical Biochemistry
  • Cell Biology
  • Physiology

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