Abstract
We assessed the validity of two screening tests [the Mini-Mental State Examination (MMSE) and the Milan Overall Dementia Assessment or (MODA)] in a population study on the prevalence of Alzheimer's disease, carried out in a small town in the north of Italy. A random sample of 1000 subjects aged 60 years or over entered the study. Subjects who scored below the cut-off points on MODA or on MMSE, or both, were further investigated with neuropsychological, laboratory and instrumental tests to ascertain a final diagnosis, which was considered as the gold standard. Our findings show that MODA has a higher sensitivity than MMSE in detecting subjects affected by dementing illnesses, while MMSE shows a higher specificity. MODA seems to be preferable to MMSE as a screening test for studies where a very high sensitivity is required.
Original language | English |
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Pages (from-to) | 289-294 |
Number of pages | 6 |
Journal | European Journal of Neurology |
Volume | 6 |
Issue number | 3 |
Publication status | Published - 1999 |
Keywords
- Dementia
- Epidemiology
- Screening
ASJC Scopus subject areas
- Clinical Neurology
- Neuroscience(all)