The Milan Overall Dementia Assessment and the Mini-Mental State Examination compared: An epidemiological investigation of dementia

Federico M. Cossa, Sergio Della Sala, Massimo Musicco, Hans Spinnler, Maria C. Ubezio

Research output: Contribution to journalArticlepeer-review

Abstract

We assessed the validity of two screening tests [the Mini-Mental State Examination (MMSE) and the Milan Overall Dementia Assessment or (MODA)] in a population study on the prevalence of Alzheimer's disease, carried out in a small town in the north of Italy. A random sample of 1000 subjects aged 60 years or over entered the study. Subjects who scored below the cut-off points on MODA or on MMSE, or both, were further investigated with neuropsychological, laboratory and instrumental tests to ascertain a final diagnosis, which was considered as the gold standard. Our findings show that MODA has a higher sensitivity than MMSE in detecting subjects affected by dementing illnesses, while MMSE shows a higher specificity. MODA seems to be preferable to MMSE as a screening test for studies where a very high sensitivity is required.

Original languageEnglish
Pages (from-to)289-294
Number of pages6
JournalEuropean Journal of Neurology
Volume6
Issue number3
Publication statusPublished - 1999

Keywords

  • Dementia
  • Epidemiology
  • Screening

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

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