The minimum information required for reporting a molecular interaction experiment (MIMIx)

Sandra Orchard, Lukasz Salwinski, Samuel Kerrien, Luisa Montecchi-Palazzi, Matthias Oesterheld, Volker Stümpflen, Arnaud Ceol, Andrew Chatr-Aryamontri, John Armstrong, Peter Woollard, John J. Salama, Susan Moore, Jérôme Wojcik, Gary D. Bader, Marc Vidal, Michael E. Cusick, Mark Gerstein, Anne Claude Gavin, Giulio Superti-Furga, Jack GreenblattJoel Bader, Peter Uetz, Mike Tyers, Pierre Legrain, Stan Fields, Nicola Mulder, Michael Gilson, Michael Niepmann, Lyle Burgoon, Javier De Las Rivas, Carlos Prieto, Victoria M. Perreau, Chris Hogue, Hans Werner Mewes, Rolf Apweiler, Ioannis Xenarios, David Eisenberg, Gianni Cesareni, Henning Hermjakob

Research output: Contribution to journalArticlepeer-review

Abstract

A wealth of molecular interaction data is available in the literature, ranging from large-scale datasets to a single interaction confirmed by several different techniques. These data are all too often reported either as free text or in tables of variable format, and are often missing key pieces of information essential for a full understanding of the experiment. Here we propose MIMIx, the minimum information required for reporting a molecular interaction experiment. Adherence to these reporting guidelines will result in publications of increased clarity and usefulness to the scientific community and will support the rapid, systematic capture of molecular interaction data in public databases, thereby improving access to valuable interaction data.

Original languageEnglish
Pages (from-to)894-898
Number of pages5
JournalNature Biotechnology
Volume25
Issue number8
DOIs
Publication statusPublished - Aug 2007

ASJC Scopus subject areas

  • Microbiology

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