The minimum information required for reporting a molecular interaction experiment (MIMIx)

Sandra Orchard, Lukasz Salwinski, Samuel Kerrien, Luisa Montecchi-Palazzi, Matthias Oesterheld, Volker Stümpflen, Arnaud Ceol, Andrew Chatr-Aryamontri, John Armstrong, Peter Woollard, John J. Salama, Susan Moore, Jérôme Wojcik, Gary D. Bader, Marc Vidal, Michael E. Cusick, Mark Gerstein, Anne Claude Gavin, Giulio Superti-Furga, Jack GreenblattJoel Bader, Peter Uetz, Mike Tyers, Pierre Legrain, Stan Fields, Nicola Mulder, Michael Gilson, Michael Niepmann, Lyle Burgoon, Javier De Las Rivas, Carlos Prieto, Victoria M. Perreau, Chris Hogue, Hans Werner Mewes, Rolf Apweiler, Ioannis Xenarios, David Eisenberg, Gianni Cesareni, Henning Hermjakob

Research output: Contribution to journalArticle

179 Citations (Scopus)

Abstract

A wealth of molecular interaction data is available in the literature, ranging from large-scale datasets to a single interaction confirmed by several different techniques. These data are all too often reported either as free text or in tables of variable format, and are often missing key pieces of information essential for a full understanding of the experiment. Here we propose MIMIx, the minimum information required for reporting a molecular interaction experiment. Adherence to these reporting guidelines will result in publications of increased clarity and usefulness to the scientific community and will support the rapid, systematic capture of molecular interaction data in public databases, thereby improving access to valuable interaction data.

Original languageEnglish
Pages (from-to)894-898
Number of pages5
JournalNature Biotechnology
Volume25
Issue number8
DOIs
Publication statusPublished - Aug 2007

Fingerprint

Molecular interactions
Publications
Databases
Guidelines
Experiments
Datasets

ASJC Scopus subject areas

  • Microbiology

Cite this

Orchard, S., Salwinski, L., Kerrien, S., Montecchi-Palazzi, L., Oesterheld, M., Stümpflen, V., ... Hermjakob, H. (2007). The minimum information required for reporting a molecular interaction experiment (MIMIx). Nature Biotechnology, 25(8), 894-898. https://doi.org/10.1038/nbt1324

The minimum information required for reporting a molecular interaction experiment (MIMIx). / Orchard, Sandra; Salwinski, Lukasz; Kerrien, Samuel; Montecchi-Palazzi, Luisa; Oesterheld, Matthias; Stümpflen, Volker; Ceol, Arnaud; Chatr-Aryamontri, Andrew; Armstrong, John; Woollard, Peter; Salama, John J.; Moore, Susan; Wojcik, Jérôme; Bader, Gary D.; Vidal, Marc; Cusick, Michael E.; Gerstein, Mark; Gavin, Anne Claude; Superti-Furga, Giulio; Greenblatt, Jack; Bader, Joel; Uetz, Peter; Tyers, Mike; Legrain, Pierre; Fields, Stan; Mulder, Nicola; Gilson, Michael; Niepmann, Michael; Burgoon, Lyle; Rivas, Javier De Las; Prieto, Carlos; Perreau, Victoria M.; Hogue, Chris; Mewes, Hans Werner; Apweiler, Rolf; Xenarios, Ioannis; Eisenberg, David; Cesareni, Gianni; Hermjakob, Henning.

In: Nature Biotechnology, Vol. 25, No. 8, 08.2007, p. 894-898.

Research output: Contribution to journalArticle

Orchard, S, Salwinski, L, Kerrien, S, Montecchi-Palazzi, L, Oesterheld, M, Stümpflen, V, Ceol, A, Chatr-Aryamontri, A, Armstrong, J, Woollard, P, Salama, JJ, Moore, S, Wojcik, J, Bader, GD, Vidal, M, Cusick, ME, Gerstein, M, Gavin, AC, Superti-Furga, G, Greenblatt, J, Bader, J, Uetz, P, Tyers, M, Legrain, P, Fields, S, Mulder, N, Gilson, M, Niepmann, M, Burgoon, L, Rivas, JDL, Prieto, C, Perreau, VM, Hogue, C, Mewes, HW, Apweiler, R, Xenarios, I, Eisenberg, D, Cesareni, G & Hermjakob, H 2007, 'The minimum information required for reporting a molecular interaction experiment (MIMIx)', Nature Biotechnology, vol. 25, no. 8, pp. 894-898. https://doi.org/10.1038/nbt1324
Orchard S, Salwinski L, Kerrien S, Montecchi-Palazzi L, Oesterheld M, Stümpflen V et al. The minimum information required for reporting a molecular interaction experiment (MIMIx). Nature Biotechnology. 2007 Aug;25(8):894-898. https://doi.org/10.1038/nbt1324
Orchard, Sandra ; Salwinski, Lukasz ; Kerrien, Samuel ; Montecchi-Palazzi, Luisa ; Oesterheld, Matthias ; Stümpflen, Volker ; Ceol, Arnaud ; Chatr-Aryamontri, Andrew ; Armstrong, John ; Woollard, Peter ; Salama, John J. ; Moore, Susan ; Wojcik, Jérôme ; Bader, Gary D. ; Vidal, Marc ; Cusick, Michael E. ; Gerstein, Mark ; Gavin, Anne Claude ; Superti-Furga, Giulio ; Greenblatt, Jack ; Bader, Joel ; Uetz, Peter ; Tyers, Mike ; Legrain, Pierre ; Fields, Stan ; Mulder, Nicola ; Gilson, Michael ; Niepmann, Michael ; Burgoon, Lyle ; Rivas, Javier De Las ; Prieto, Carlos ; Perreau, Victoria M. ; Hogue, Chris ; Mewes, Hans Werner ; Apweiler, Rolf ; Xenarios, Ioannis ; Eisenberg, David ; Cesareni, Gianni ; Hermjakob, Henning. / The minimum information required for reporting a molecular interaction experiment (MIMIx). In: Nature Biotechnology. 2007 ; Vol. 25, No. 8. pp. 894-898.
@article{dc9405fbfea84d7c9048de34b2129d5c,
title = "The minimum information required for reporting a molecular interaction experiment (MIMIx)",
abstract = "A wealth of molecular interaction data is available in the literature, ranging from large-scale datasets to a single interaction confirmed by several different techniques. These data are all too often reported either as free text or in tables of variable format, and are often missing key pieces of information essential for a full understanding of the experiment. Here we propose MIMIx, the minimum information required for reporting a molecular interaction experiment. Adherence to these reporting guidelines will result in publications of increased clarity and usefulness to the scientific community and will support the rapid, systematic capture of molecular interaction data in public databases, thereby improving access to valuable interaction data.",
author = "Sandra Orchard and Lukasz Salwinski and Samuel Kerrien and Luisa Montecchi-Palazzi and Matthias Oesterheld and Volker St{\"u}mpflen and Arnaud Ceol and Andrew Chatr-Aryamontri and John Armstrong and Peter Woollard and Salama, {John J.} and Susan Moore and J{\'e}r{\^o}me Wojcik and Bader, {Gary D.} and Marc Vidal and Cusick, {Michael E.} and Mark Gerstein and Gavin, {Anne Claude} and Giulio Superti-Furga and Jack Greenblatt and Joel Bader and Peter Uetz and Mike Tyers and Pierre Legrain and Stan Fields and Nicola Mulder and Michael Gilson and Michael Niepmann and Lyle Burgoon and Rivas, {Javier De Las} and Carlos Prieto and Perreau, {Victoria M.} and Chris Hogue and Mewes, {Hans Werner} and Rolf Apweiler and Ioannis Xenarios and David Eisenberg and Gianni Cesareni and Henning Hermjakob",
year = "2007",
month = "8",
doi = "10.1038/nbt1324",
language = "English",
volume = "25",
pages = "894--898",
journal = "Biotechnology",
issn = "1087-0156",
publisher = "Nature Publishing Group",
number = "8",

}

TY - JOUR

T1 - The minimum information required for reporting a molecular interaction experiment (MIMIx)

AU - Orchard, Sandra

AU - Salwinski, Lukasz

AU - Kerrien, Samuel

AU - Montecchi-Palazzi, Luisa

AU - Oesterheld, Matthias

AU - Stümpflen, Volker

AU - Ceol, Arnaud

AU - Chatr-Aryamontri, Andrew

AU - Armstrong, John

AU - Woollard, Peter

AU - Salama, John J.

AU - Moore, Susan

AU - Wojcik, Jérôme

AU - Bader, Gary D.

AU - Vidal, Marc

AU - Cusick, Michael E.

AU - Gerstein, Mark

AU - Gavin, Anne Claude

AU - Superti-Furga, Giulio

AU - Greenblatt, Jack

AU - Bader, Joel

AU - Uetz, Peter

AU - Tyers, Mike

AU - Legrain, Pierre

AU - Fields, Stan

AU - Mulder, Nicola

AU - Gilson, Michael

AU - Niepmann, Michael

AU - Burgoon, Lyle

AU - Rivas, Javier De Las

AU - Prieto, Carlos

AU - Perreau, Victoria M.

AU - Hogue, Chris

AU - Mewes, Hans Werner

AU - Apweiler, Rolf

AU - Xenarios, Ioannis

AU - Eisenberg, David

AU - Cesareni, Gianni

AU - Hermjakob, Henning

PY - 2007/8

Y1 - 2007/8

N2 - A wealth of molecular interaction data is available in the literature, ranging from large-scale datasets to a single interaction confirmed by several different techniques. These data are all too often reported either as free text or in tables of variable format, and are often missing key pieces of information essential for a full understanding of the experiment. Here we propose MIMIx, the minimum information required for reporting a molecular interaction experiment. Adherence to these reporting guidelines will result in publications of increased clarity and usefulness to the scientific community and will support the rapid, systematic capture of molecular interaction data in public databases, thereby improving access to valuable interaction data.

AB - A wealth of molecular interaction data is available in the literature, ranging from large-scale datasets to a single interaction confirmed by several different techniques. These data are all too often reported either as free text or in tables of variable format, and are often missing key pieces of information essential for a full understanding of the experiment. Here we propose MIMIx, the minimum information required for reporting a molecular interaction experiment. Adherence to these reporting guidelines will result in publications of increased clarity and usefulness to the scientific community and will support the rapid, systematic capture of molecular interaction data in public databases, thereby improving access to valuable interaction data.

UR - http://www.scopus.com/inward/record.url?scp=34249107988&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=34249107988&partnerID=8YFLogxK

U2 - 10.1038/nbt1324

DO - 10.1038/nbt1324

M3 - Article

C2 - 17687370

AN - SCOPUS:34249107988

VL - 25

SP - 894

EP - 898

JO - Biotechnology

JF - Biotechnology

SN - 1087-0156

IS - 8

ER -