The molecular basis of thyroid epithelial tumorigenesis

Italia Bongarzone, Marco A. Pierotti

Research output: Contribution to journalArticle

Abstract

Significant alterations in gene sequences, expression levels and protein structures have been associated with specific types of thyroid epithelial tumorigenesis. Recent revolutionary changes in molecular biology have spanned the disciplines of genomics and proteomics, which systematically generate and analyze the information about genomes, gene transcripts, proteins and their functions in a global, comprehensive manner. The application of these approaches will better discriminate between thyroid tumor subtypes that are not recognizable when traditional pathological criteria are used.

Original languageEnglish
Pages (from-to)514-516
Number of pages3
JournalTumori
Volume89
Issue number5
Publication statusPublished - Sep 2003

Keywords

  • Changes in molecular biology
  • Thyroid cancer
  • Tumorigenesis

ASJC Scopus subject areas

  • Cancer Research

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