The Molecular Basis of Von Willebrand Disease

Research output: Chapter in Book/Report/Conference proceedingChapter

Original languageEnglish
Title of host publicationMolecular Hematology: Third Edition
PublisherWiley-Blackwell
Pages233-245
Number of pages13
ISBN (Print)9781405182317
DOIs
Publication statusPublished - Mar 10 2010

Keywords

  • Gene encoding VWF-mapped on chromosome 12
  • Molecular basis of von Willebrand disease
  • Transfusional therapy with plasma products containing FVIII and VWF-treatment of choice
  • Type 2 VWD-approximately 20% of all VWD cases
  • Type 3 VWD, autosomal recessive severe disorder-and nearly complete absence of VWF
  • Von Willebrand disease (VWD)-common inherited bleeding disorder
  • Von Willebrand disease and its classification
  • Von Willebrand factor in primary hemostasis
  • VWD and deficiency or multimeric plasma glycoprotein dysfunction of von Willebrand factor (VWF)
  • VWF multimer synthesis and subcellular localization of post-translational modification events

ASJC Scopus subject areas

  • Medicine(all)

Cite this