La mutazione A3243G nel mtDNA non è una causa frequente di Emicrania

Translated title of the contribution: The mtDNA A3243G mutation is not frequent in Migraineurs

D. Fortini, G. Comanducci, B. Martini, G. S. Grieco, A. Costa, M. G. Buzzi, G. Nappi, C. Casali, F. M. Santorelli

Research output: Contribution to journalArticlepeer-review


We searched for the mtDNA A3243G mutation ("MELAS" mutation) in 46 migraneurs with or without aura presenting positive family history in the maternal lineage. The goal of the study was to confirm the determine the role of an oxidative-phosphorilation disfunction in the pathogenesis of some type of migraine and to verify whether migraine is a monosintomatic form of the MELAS syndrome. We did not find the A3243G mutation in any of our patients. These results suggest that there is no association between migraine and mutation of mtDNA.

Translated title of the contributionThe mtDNA A3243G mutation is not frequent in Migraineurs
Original languageItalian
Pages (from-to)129-133
Number of pages5
JournalConfinia Cephalalgica
Issue number3
Publication statusPublished - 2000

ASJC Scopus subject areas

  • Clinical Neurology


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