The neural basis of aphasia rehabilitation: Evidence from neuroimaging and neurostimulation

Stefano F. Cappa

Research output: Contribution to journalArticlepeer-review


This article is a selective review of functional imaging investigations and brain stimulation studies addressing the neural mechanisms of recovery of strokeassociated aphasia. The imaging results show that aphasia recovery is associated with a complex pattern of brain reorganisation, involving both ipsilateral and contralateral brain regions, which is modulated by lesion size and site, time post-onset, type of training, and language task. The information provided by the imaging investigations needs to be integrated with the results of brain stimulation studies, in order to specify the most effective protocols in term of modality, locus and timing of stimulation. Further studies, using multiple imaging and neuromodulation approaches, are required to reach sound conclusions about the potential usefulness of brain stimulation approaches as an adjunct to aphasia rehabilitation.

Original languageEnglish
Pages (from-to)742-754
Number of pages13
JournalNeuropsychological Rehabilitation
Issue number5
Publication statusPublished - 2011


  • Aphasia
  • Functional magnetic resonance
  • Recovery
  • Transcranial direct current stimulation
  • Transcranial magnetic stimulation

ASJC Scopus subject areas

  • Applied Psychology
  • Neuropsychology and Physiological Psychology
  • Rehabilitation
  • Arts and Humanities (miscellaneous)

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