The neural stem cells

Stefano Pluchino, Marco Bacigaluppi, Elena Brini, Erica Butti, Chiara Cossetti, Melania Cusimano, Lucia Zanotti, Gianvito Martino

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Neural stem cells represent a heterogeneous population of mitotically active, self-renewing and multipotent cells of both the developing and the adult central nervous system (CNS) showing complex patterns of gene expression that may vary in both space and time. Endogenous stem cells residing within CNS germinal niches might concur to nervous system repair owing to their ability to drive neurogenesis and gliogenesis during adulthood. Nevertheless, self-renewal, proliferation, migration and differentiation of CNS stem cells may significantly vary upon different types (e.g. acute vs chronic, focal vs multifocal) of CNS injury. In this chapter we address several aspects of neural stem cell pathophysiology.

Original languageEnglish
Title of host publicationCell Cycle Regulation and Differentiation in Cardiovascular and Neural Systems
PublisherSpringer New York
Pages71-78
Number of pages8
ISBN (Print)9781603271523
DOIs
Publication statusPublished - 2010

Fingerprint

Neural Stem Cells
Central Nervous System
Stem Cells
Nervous System Trauma
Neurogenesis
Nervous System
Gene Expression
Population

Keywords

  • Glia
  • Nervous system disorders
  • Neural progenitor cells
  • Neural stem cell transplantation
  • Neurogenesis
  • Neurons

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Pluchino, S., Bacigaluppi, M., Brini, E., Butti, E., Cossetti, C., Cusimano, M., ... Martino, G. (2010). The neural stem cells. In Cell Cycle Regulation and Differentiation in Cardiovascular and Neural Systems (pp. 71-78). Springer New York. https://doi.org/10.1007/978-1-60327-153-0_4

The neural stem cells. / Pluchino, Stefano; Bacigaluppi, Marco; Brini, Elena; Butti, Erica; Cossetti, Chiara; Cusimano, Melania; Zanotti, Lucia; Martino, Gianvito.

Cell Cycle Regulation and Differentiation in Cardiovascular and Neural Systems. Springer New York, 2010. p. 71-78.

Research output: Chapter in Book/Report/Conference proceedingChapter

Pluchino, S, Bacigaluppi, M, Brini, E, Butti, E, Cossetti, C, Cusimano, M, Zanotti, L & Martino, G 2010, The neural stem cells. in Cell Cycle Regulation and Differentiation in Cardiovascular and Neural Systems. Springer New York, pp. 71-78. https://doi.org/10.1007/978-1-60327-153-0_4
Pluchino S, Bacigaluppi M, Brini E, Butti E, Cossetti C, Cusimano M et al. The neural stem cells. In Cell Cycle Regulation and Differentiation in Cardiovascular and Neural Systems. Springer New York. 2010. p. 71-78 https://doi.org/10.1007/978-1-60327-153-0_4
Pluchino, Stefano ; Bacigaluppi, Marco ; Brini, Elena ; Butti, Erica ; Cossetti, Chiara ; Cusimano, Melania ; Zanotti, Lucia ; Martino, Gianvito. / The neural stem cells. Cell Cycle Regulation and Differentiation in Cardiovascular and Neural Systems. Springer New York, 2010. pp. 71-78
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