The NM23 gene maps to human chromosome band 17q22 and shows a restriction fragment length polymorphism with BglII

L. Varesco, M. A. Caligo, P. Simi, D. M. Black, V. Nardini, L. Casarino, M. Rocchi, G. Ferrara, E. Solomon, G. Bevilacqua

Research output: Contribution to journalArticle

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Abstract

The NM23-HI gene is a putative tumor suppressor gene that may be important in the metastatic process. Recent genetic and immunological data indicate that the NM23-HI gene encodes a protein with nucleoside diphosphate (NDP) kinase activity. The mapping of NM23-HI by panels of rodent-human somatic cell hybrids and in situ hybridization showed that the gene is located in human chromosome band 17q22. A two-allele polymorphism with BglII was demonstrated.

Original languageEnglish
Pages (from-to)84-88
Number of pages5
JournalGenes Chromosomes and Cancer
Volume4
Issue number1
Publication statusPublished - 1992

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Human Chromosomes
Restriction Fragment Length Polymorphisms
Nucleoside-Diphosphate Kinase
Genes
Hybrid Cells
Tumor Suppressor Genes
In Situ Hybridization
Rodentia
Alleles
Proteins

ASJC Scopus subject areas

  • Cancer Research
  • Genetics

Cite this

Varesco, L., Caligo, M. A., Simi, P., Black, D. M., Nardini, V., Casarino, L., ... Bevilacqua, G. (1992). The NM23 gene maps to human chromosome band 17q22 and shows a restriction fragment length polymorphism with BglII. Genes Chromosomes and Cancer, 4(1), 84-88.

The NM23 gene maps to human chromosome band 17q22 and shows a restriction fragment length polymorphism with BglII. / Varesco, L.; Caligo, M. A.; Simi, P.; Black, D. M.; Nardini, V.; Casarino, L.; Rocchi, M.; Ferrara, G.; Solomon, E.; Bevilacqua, G.

In: Genes Chromosomes and Cancer, Vol. 4, No. 1, 1992, p. 84-88.

Research output: Contribution to journalArticle

Varesco, L, Caligo, MA, Simi, P, Black, DM, Nardini, V, Casarino, L, Rocchi, M, Ferrara, G, Solomon, E & Bevilacqua, G 1992, 'The NM23 gene maps to human chromosome band 17q22 and shows a restriction fragment length polymorphism with BglII', Genes Chromosomes and Cancer, vol. 4, no. 1, pp. 84-88.
Varesco, L. ; Caligo, M. A. ; Simi, P. ; Black, D. M. ; Nardini, V. ; Casarino, L. ; Rocchi, M. ; Ferrara, G. ; Solomon, E. ; Bevilacqua, G. / The NM23 gene maps to human chromosome band 17q22 and shows a restriction fragment length polymorphism with BglII. In: Genes Chromosomes and Cancer. 1992 ; Vol. 4, No. 1. pp. 84-88.
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