The NM23 gene maps to human chromosome band 17q22 and shows a restriction fragment length polymorphism with BglII

L. Varesco, M. A. Caligo, P. Simi, D. M. Black, V. Nardini, L. Casarino, M. Rocchi, G. Ferrara, E. Solomon, G. Bevilacqua

Research output: Contribution to journalArticle

Abstract

The NM23-HI gene is a putative tumor suppressor gene that may be important in the metastatic process. Recent genetic and immunological data indicate that the NM23-HI gene encodes a protein with nucleoside diphosphate (NDP) kinase activity. The mapping of NM23-HI by panels of rodent-human somatic cell hybrids and in situ hybridization showed that the gene is located in human chromosome band 17q22. A two-allele polymorphism with BglII was demonstrated.

Original languageEnglish
Pages (from-to)84-88
Number of pages5
JournalGenes Chromosomes and Cancer
Volume4
Issue number1
Publication statusPublished - 1992

ASJC Scopus subject areas

  • Cancer Research
  • Genetics

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    Varesco, L., Caligo, M. A., Simi, P., Black, D. M., Nardini, V., Casarino, L., Rocchi, M., Ferrara, G., Solomon, E., & Bevilacqua, G. (1992). The NM23 gene maps to human chromosome band 17q22 and shows a restriction fragment length polymorphism with BglII. Genes Chromosomes and Cancer, 4(1), 84-88.