The NM23-HI gene is a putative tumor suppressor gene that may be important in the metastatic process. Recent genetic and immunological data indicate that the NM23-HI gene encodes a protein with nucleoside diphosphate (NDP) kinase activity. The mapping of NM23-HI by panels of rodent-human somatic cell hybrids and in situ hybridization showed that the gene is located in human chromosome band 17q22. A two-allele polymorphism with BglII was demonstrated.
|Number of pages||5|
|Journal||Genes Chromosomes and Cancer|
|Publication status||Published - 1992|
ASJC Scopus subject areas
- Cancer Research