The novel swine-origin H1N1 influenza A virus riddle: Is it a domestic bird H1N1-derived virus?

Muhammed Babamr-Mina, Salvatore Dimonte, Massimo Ciccozzi, Carlo Federico Perno, Marco Ciotti

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

To understand the role of domestic birds in the 2009 H1N1 influenza A outbreak, a phylogenetic analysis of hemagglutinin, neuraminidase and matrix protein genes from human, avian and swine H1N1 viruses was carried out Analysis of the H1 sequences revealed that the virus evolved most likely from American swine as well as intermixing between Asian swine and American domestic bird H1N1 viruses. Neuroaminidase and matrix protein analysis showed that the H1N1 2009 viruses were more closely related to the H1N1 isolates from Euro-Asiatic domestic birds and swine than wild birds. Domestic birds could act as intermediate hosts of H1N1 reassortants.

Original languageEnglish
Pages (from-to)77-81
Number of pages5
JournalNew Microbiologica
Volume33
Issue number1
Publication statusPublished - Jan 2010

Fingerprint

H1N1 Subtype Influenza A Virus
Birds
Swine
Asian Americans
Hemagglutinins
Neuraminidase
Human Influenza
Disease Outbreaks
Sequence Analysis
Proteins
Viruses

Keywords

  • Avian flu
  • Influenza pandemic
  • Molecular evolution
  • Phylogenetic analysis
  • Swine flu

ASJC Scopus subject areas

  • Microbiology (medical)

Cite this

The novel swine-origin H1N1 influenza A virus riddle : Is it a domestic bird H1N1-derived virus? / Babamr-Mina, Muhammed; Dimonte, Salvatore; Ciccozzi, Massimo; Perno, Carlo Federico; Ciotti, Marco.

In: New Microbiologica, Vol. 33, No. 1, 01.2010, p. 77-81.

Research output: Contribution to journalArticle

Babamr-Mina, M, Dimonte, S, Ciccozzi, M, Perno, CF & Ciotti, M 2010, 'The novel swine-origin H1N1 influenza A virus riddle: Is it a domestic bird H1N1-derived virus?', New Microbiologica, vol. 33, no. 1, pp. 77-81.
Babamr-Mina, Muhammed ; Dimonte, Salvatore ; Ciccozzi, Massimo ; Perno, Carlo Federico ; Ciotti, Marco. / The novel swine-origin H1N1 influenza A virus riddle : Is it a domestic bird H1N1-derived virus?. In: New Microbiologica. 2010 ; Vol. 33, No. 1. pp. 77-81.
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