The old and new coeliac disease

A. Ventura, S. Martelossi

Research output: Contribution to journalArticle

Abstract

Coeliac disease is a well known disorder, which is considered by pediatricians as a chronic gluten-dependent enteropathy. Until a few years ago the disorder was considered rather rare but clinically well defined. Its diagnosis required in the past three intestinal biopsies aimed at demonstrating the subatrophy of the intestinal mucosa and its dependence on the gluten intake. The results of the research especially in the immunogenetic field and the availability of new sensible, specific and easy to be performed screening tests, such as antigluten and antiendomysium antibodies, led to an explosion of new scientific data. The latter brought all the previous firm beliefs up for discussion again and led to consider the coeliac disease a fascinating model of human physiopathology.

Original languageEnglish
Pages (from-to)87-94
Number of pages8
JournalEuropean Journal of Pediatric Dermatology
Volume5
Issue number2
Publication statusPublished - 1995

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Keywords

  • coeliac disease
  • gluten
  • immunogenetics

ASJC Scopus subject areas

  • Dermatology
  • Pediatrics, Perinatology, and Child Health

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