The outcome of intra-aortic balloon pump support in acute myocardial infarction complicated by cardiogenic shock according to the type of revascularization: A comprehensive meta-analysis

Francesco Romeo, Maria Cristina Acconcia, Domenico Sergi, Alessia Romeo, Saverio Muscoli, Serafina Valente, Gian Franco Gensini, Flavia Chiarotti, Quintilio Caretta

Research output: Contribution to journalArticle

38 Citations (Scopus)

Abstract

Aims Despite the recommendations of the current guidelines, scientific evidence continue to challenge the effectiveness of intra-aortic balloon pump (IABP) in acute myocardial infarction (AMI) complicated by cardiogenic shock. Moreover, 2 recent meta-analyses showed contrasting results. The aim of this study is to test the effect of IABP according to the type of therapeutic treatment of AMI: percutaneous coronary intervention (PCI), thrombolytic therapy (TT), or medical therapy without reperfusion. Articles published from January 1, 1986, to December 31, 2012, were collected and analyzed by meta-analysis. Methods and results We evaluated the IABP impact on inhospital mortality, on safety end points (stroke, severe bleeding) and long-term survival, using risk ratio (RR) and risk difference (RD) estimates. We found that the risk of death was (i) not significantly different between the IABP and control groups (RR 0.95, P =.52; RD -0.04, P =.28), (ii) significantly reduced in the TT subgroup (RR 0.77, P

Original languageEnglish
Pages (from-to)679-692
Number of pages14
JournalAmerican Heart Journal
Volume165
Issue number5
DOIs
Publication statusPublished - May 2013

Fingerprint

Cardiogenic Shock
Meta-Analysis
Thrombolytic Therapy
Odds Ratio
Myocardial Infarction
Percutaneous Coronary Intervention
Hospital Mortality
Reperfusion
Therapeutics
Stroke
Guidelines
Hemorrhage
Safety
Control Groups

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

The outcome of intra-aortic balloon pump support in acute myocardial infarction complicated by cardiogenic shock according to the type of revascularization : A comprehensive meta-analysis. / Romeo, Francesco; Acconcia, Maria Cristina; Sergi, Domenico; Romeo, Alessia; Muscoli, Saverio; Valente, Serafina; Gensini, Gian Franco; Chiarotti, Flavia; Caretta, Quintilio.

In: American Heart Journal, Vol. 165, No. 5, 05.2013, p. 679-692.

Research output: Contribution to journalArticle

Romeo, Francesco ; Acconcia, Maria Cristina ; Sergi, Domenico ; Romeo, Alessia ; Muscoli, Saverio ; Valente, Serafina ; Gensini, Gian Franco ; Chiarotti, Flavia ; Caretta, Quintilio. / The outcome of intra-aortic balloon pump support in acute myocardial infarction complicated by cardiogenic shock according to the type of revascularization : A comprehensive meta-analysis. In: American Heart Journal. 2013 ; Vol. 165, No. 5. pp. 679-692.
@article{5f244235ea4e4180ab2f1f3dd3b107df,
title = "The outcome of intra-aortic balloon pump support in acute myocardial infarction complicated by cardiogenic shock according to the type of revascularization: A comprehensive meta-analysis",
abstract = "Aims Despite the recommendations of the current guidelines, scientific evidence continue to challenge the effectiveness of intra-aortic balloon pump (IABP) in acute myocardial infarction (AMI) complicated by cardiogenic shock. Moreover, 2 recent meta-analyses showed contrasting results. The aim of this study is to test the effect of IABP according to the type of therapeutic treatment of AMI: percutaneous coronary intervention (PCI), thrombolytic therapy (TT), or medical therapy without reperfusion. Articles published from January 1, 1986, to December 31, 2012, were collected and analyzed by meta-analysis. Methods and results We evaluated the IABP impact on inhospital mortality, on safety end points (stroke, severe bleeding) and long-term survival, using risk ratio (RR) and risk difference (RD) estimates. We found that the risk of death was (i) not significantly different between the IABP and control groups (RR 0.95, P =.52; RD -0.04, P =.28), (ii) significantly reduced in the TT subgroup (RR 0.77, P",
author = "Francesco Romeo and Acconcia, {Maria Cristina} and Domenico Sergi and Alessia Romeo and Saverio Muscoli and Serafina Valente and Gensini, {Gian Franco} and Flavia Chiarotti and Quintilio Caretta",
year = "2013",
month = "5",
doi = "10.1016/j.ahj.2013.02.020",
language = "English",
volume = "165",
pages = "679--692",
journal = "American Heart Journal",
issn = "0002-8703",
publisher = "Mosby Inc.",
number = "5",

}

TY - JOUR

T1 - The outcome of intra-aortic balloon pump support in acute myocardial infarction complicated by cardiogenic shock according to the type of revascularization

T2 - A comprehensive meta-analysis

AU - Romeo, Francesco

AU - Acconcia, Maria Cristina

AU - Sergi, Domenico

AU - Romeo, Alessia

AU - Muscoli, Saverio

AU - Valente, Serafina

AU - Gensini, Gian Franco

AU - Chiarotti, Flavia

AU - Caretta, Quintilio

PY - 2013/5

Y1 - 2013/5

N2 - Aims Despite the recommendations of the current guidelines, scientific evidence continue to challenge the effectiveness of intra-aortic balloon pump (IABP) in acute myocardial infarction (AMI) complicated by cardiogenic shock. Moreover, 2 recent meta-analyses showed contrasting results. The aim of this study is to test the effect of IABP according to the type of therapeutic treatment of AMI: percutaneous coronary intervention (PCI), thrombolytic therapy (TT), or medical therapy without reperfusion. Articles published from January 1, 1986, to December 31, 2012, were collected and analyzed by meta-analysis. Methods and results We evaluated the IABP impact on inhospital mortality, on safety end points (stroke, severe bleeding) and long-term survival, using risk ratio (RR) and risk difference (RD) estimates. We found that the risk of death was (i) not significantly different between the IABP and control groups (RR 0.95, P =.52; RD -0.04, P =.28), (ii) significantly reduced in the TT subgroup (RR 0.77, P

AB - Aims Despite the recommendations of the current guidelines, scientific evidence continue to challenge the effectiveness of intra-aortic balloon pump (IABP) in acute myocardial infarction (AMI) complicated by cardiogenic shock. Moreover, 2 recent meta-analyses showed contrasting results. The aim of this study is to test the effect of IABP according to the type of therapeutic treatment of AMI: percutaneous coronary intervention (PCI), thrombolytic therapy (TT), or medical therapy without reperfusion. Articles published from January 1, 1986, to December 31, 2012, were collected and analyzed by meta-analysis. Methods and results We evaluated the IABP impact on inhospital mortality, on safety end points (stroke, severe bleeding) and long-term survival, using risk ratio (RR) and risk difference (RD) estimates. We found that the risk of death was (i) not significantly different between the IABP and control groups (RR 0.95, P =.52; RD -0.04, P =.28), (ii) significantly reduced in the TT subgroup (RR 0.77, P

UR - http://www.scopus.com/inward/record.url?scp=84876814456&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84876814456&partnerID=8YFLogxK

U2 - 10.1016/j.ahj.2013.02.020

DO - 10.1016/j.ahj.2013.02.020

M3 - Article

C2 - 23622904

AN - SCOPUS:84876814456

VL - 165

SP - 679

EP - 692

JO - American Heart Journal

JF - American Heart Journal

SN - 0002-8703

IS - 5

ER -