The palliative prognostic score and survival in patients with advanced solid tumors receiving chemotherapy

Davide Tassinari, Luigi Montanari, Marco Maltoni, Michela Ballardini, Alessandra Piancastelli, Marco Musi, Giampiero Porzio, Vincenzo Minotti, Augusto Caraceni, Barbara Poggi, Anna Stella, Federica Aielli, Emanuela Scarpi

Research output: Contribution to journalArticlepeer-review

Abstract

Purpose: To evaluate the accuracy of the Palliative Prognostic Score (PaP score) in selecting metastatic gastrointestinal or nonsmall-cell lung cancer patients candidate to palliative chemotherapy. Materials and methods: The PaP score was calculated in 173 patients with advanced, pretreated gastrointestinal or nonsmall-cell lung cancer before starting a further line of chemotherapy with palliative aim. Symptom distress score was calculated using the Edmonton Symptom Assessment System (ESAS) before every course of chemotherapy. Univariate analysis of survival was performed using the logrank test; multivariate analysis was performed using the Cox regression model. Symptom distress scores were compared using multivariate analysis of variance test for repeated measures, and overall symptom distress score was compared using analysis of variance test for repeated measures. Results: Overall median survival was 26 weeks; in PaP score class A it was 32 weeks, and in class B 8 weeks (p

Original languageEnglish
Pages (from-to)359-370
Number of pages12
JournalSupportive Care in Cancer
Volume16
Issue number4
DOIs
Publication statusPublished - Apr 2008

Keywords

  • Metastatic cancer
  • Nonsmall-cell lung cancer
  • Palliative prognostic score

ASJC Scopus subject areas

  • Oncology
  • Nursing(all)

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