The PE multigene family: A 'molecular mantra' for mycobacteria

Michael J. Brennan; Giovanni Delogu

doi:10.1016/S0966-842X(02)02335-1

The PE multigene family: A 'molecular mantra' for mycobacteria

Michael J. Brennan, Giovanni Delogu

Istituto Nazionale per le Malattie Infettive Lazzaro Spallanzani

Research output: Contribution to journal › Article

Abstract

The PE multigene family of Mycobacterium tuberculosis is remarkable in that it is composed of approximately 100 highly homologous genes that are found only in mycobacteria. Early evidence suggests that proteins encoded by certain members of this gene family could be present in the mycobacterial cell wall, impact antigen-presentation pathways and the ensuing host immune responses, and also provide a mechanism for generating antigenic diversity in mycobacteria.

Original language	English
Pages (from-to)	246-249
Number of pages	4
Journal	Trends in Microbiology
Volume	10
Issue number	5
DOIs	https://doi.org/10.1016/S0966-842X(02)02335-1
Publication status	Published - May 1 2002

ASJC Scopus subject areas

Microbiology
Infectious Diseases

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Brennan, M. J., & Delogu, G. (2002). The PE multigene family: A 'molecular mantra' for mycobacteria. Trends in Microbiology, 10(5), 246-249. https://doi.org/10.1016/S0966-842X(02)02335-1

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