The PE multigene family: A 'molecular mantra' for mycobacteria

Michael J. Brennan, Giovanni Delogu

Research output: Contribution to journalArticlepeer-review


The PE multigene family of Mycobacterium tuberculosis is remarkable in that it is composed of approximately 100 highly homologous genes that are found only in mycobacteria. Early evidence suggests that proteins encoded by certain members of this gene family could be present in the mycobacterial cell wall, impact antigen-presentation pathways and the ensuing host immune responses, and also provide a mechanism for generating antigenic diversity in mycobacteria.

Original languageEnglish
Pages (from-to)246-249
Number of pages4
JournalTrends in Microbiology
Issue number5
Publication statusPublished - May 1 2002

ASJC Scopus subject areas

  • Microbiology
  • Infectious Diseases


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