The pharmacologic elegance of inhibiting cholesterol absorption and synthesis while providing a homeostatic balance

Alberico L. Catapano

doi:10.1111/j.1472-8206.2007.00534.x

The pharmacologic elegance of inhibiting cholesterol absorption and synthesis while providing a homeostatic balance

Alberico L. Catapano

IRCCS Multimedica

Research output: Contribution to journal › Article › peer-review

Abstract

The recent discoveries on the concerted role of several mechanisms involved in regulating the balance of body cholesterol highlight the role of intestinal absorption. Selective modulators of intestinal cholesterol absorption are available that offer a new pharmacologic approach to the modulation of total body cholesterol homeostasis and to a more effective reduction of low-density-lipoprotein cholesterol.

Original language	English
Pages (from-to)	21-26
Number of pages	6
Journal	Fundamental and Clinical Pharmacology
Volume	21
Issue number	SUPPL. 2
DOIs	https://doi.org/10.1111/j.1472-8206.2007.00534.x
Publication status	Published - Nov 2007

Keywords

Intestine
LDL
Liver
NPC1L1

ASJC Scopus subject areas

Pharmacology
Pharmacology (medical)

Access to Document

10.1111/j.1472-8206.2007.00534.x

Cite this

@article{2de8814e6a64453dbffb297bad9519af,

title = "The pharmacologic elegance of inhibiting cholesterol absorption and synthesis while providing a homeostatic balance",

abstract = "The recent discoveries on the concerted role of several mechanisms involved in regulating the balance of body cholesterol highlight the role of intestinal absorption. Selective modulators of intestinal cholesterol absorption are available that offer a new pharmacologic approach to the modulation of total body cholesterol homeostasis and to a more effective reduction of low-density-lipoprotein cholesterol.",

keywords = "Intestine, LDL, Liver, NPC1L1",

author = "Catapano, {Alberico L.}",

year = "2007",

month = nov,

doi = "10.1111/j.1472-8206.2007.00534.x",

language = "English",

volume = "21",

pages = "21--26",

journal = "Fundamental and Clinical Pharmacology",

issn = "0767-3981",

publisher = "Wiley-Blackwell",

number = "SUPPL. 2",

}

TY - JOUR

T1 - The pharmacologic elegance of inhibiting cholesterol absorption and synthesis while providing a homeostatic balance

AU - Catapano, Alberico L.

PY - 2007/11

Y1 - 2007/11

N2 - The recent discoveries on the concerted role of several mechanisms involved in regulating the balance of body cholesterol highlight the role of intestinal absorption. Selective modulators of intestinal cholesterol absorption are available that offer a new pharmacologic approach to the modulation of total body cholesterol homeostasis and to a more effective reduction of low-density-lipoprotein cholesterol.

AB - The recent discoveries on the concerted role of several mechanisms involved in regulating the balance of body cholesterol highlight the role of intestinal absorption. Selective modulators of intestinal cholesterol absorption are available that offer a new pharmacologic approach to the modulation of total body cholesterol homeostasis and to a more effective reduction of low-density-lipoprotein cholesterol.

KW - Intestine

KW - LDL

KW - Liver

KW - NPC1L1

UR - http://www.scopus.com/inward/record.url?scp=36248957625&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=36248957625&partnerID=8YFLogxK

U2 - 10.1111/j.1472-8206.2007.00534.x

DO - 10.1111/j.1472-8206.2007.00534.x

M3 - Article

C2 - 18001316

AN - SCOPUS:36248957625

VL - 21

SP - 21

EP - 26

JO - Fundamental and Clinical Pharmacology

JF - Fundamental and Clinical Pharmacology

SN - 0767-3981

IS - SUPPL. 2

ER -

The pharmacologic elegance of inhibiting cholesterol absorption and synthesis while providing a homeostatic balance

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this