The pharmacologic elegance of inhibiting cholesterol absorption and synthesis while providing a homeostatic balance

Research output: Contribution to journalArticle

Abstract

The recent discoveries on the concerted role of several mechanisms involved in regulating the balance of body cholesterol highlight the role of intestinal absorption. Selective modulators of intestinal cholesterol absorption are available that offer a new pharmacologic approach to the modulation of total body cholesterol homeostasis and to a more effective reduction of low-density-lipoprotein cholesterol.

Original languageEnglish
Pages (from-to)21-26
Number of pages6
JournalFundamental and Clinical Pharmacology
Volume21
Issue numberSUPPL. 2
DOIs
Publication statusPublished - Nov 2007

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Cholesterol
Intestinal Absorption
LDL Cholesterol
Homeostasis

Keywords

  • Intestine
  • LDL
  • Liver
  • NPC1L1

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)

Cite this

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