The pharmacologic elegance of inhibiting cholesterol absorption and synthesis while providing a homeostatic balance

Alberico L. Catapano

doi:10.1111/j.1472-8206.2007.00534.x

The pharmacologic elegance of inhibiting cholesterol absorption and synthesis while providing a homeostatic balance

Alberico L. Catapano

IRCCS Multimedica

Research output: Contribution to journal › Article

Abstract

The recent discoveries on the concerted role of several mechanisms involved in regulating the balance of body cholesterol highlight the role of intestinal absorption. Selective modulators of intestinal cholesterol absorption are available that offer a new pharmacologic approach to the modulation of total body cholesterol homeostasis and to a more effective reduction of low-density-lipoprotein cholesterol.

Original language	English
Pages (from-to)	21-26
Number of pages	6
Journal	Fundamental and Clinical Pharmacology
Volume	21
Issue number	SUPPL. 2
DOIs	https://doi.org/10.1111/j.1472-8206.2007.00534.x
Publication status	Published - Nov 2007

Keywords

Intestine
LDL
Liver
NPC1L1

ASJC Scopus subject areas

Pharmacology
Pharmacology (medical)

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10.1111/j.1472-8206.2007.00534.x

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Catapano, A. L. (2007). The pharmacologic elegance of inhibiting cholesterol absorption and synthesis while providing a homeostatic balance. Fundamental and Clinical Pharmacology, 21(SUPPL. 2), 21-26. https://doi.org/10.1111/j.1472-8206.2007.00534.x

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