Abstract
The recent discoveries on the concerted role of several mechanisms involved in regulating the balance of body cholesterol highlight the role of intestinal absorption. Selective modulators of intestinal cholesterol absorption are available that offer a new pharmacologic approach to the modulation of total body cholesterol homeostasis and to a more effective reduction of low-density-lipoprotein cholesterol.
| Original language | English |
|---|---|
| Pages (from-to) | 21-26 |
| Number of pages | 6 |
| Journal | Fundamental and Clinical Pharmacology |
| Volume | 21 |
| Issue number | SUPPL. 2 |
| DOIs | |
| Publication status | Published - Nov 2007 |
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Keywords
- Intestine
- LDL
- Liver
- NPC1L1
ASJC Scopus subject areas
- Pharmacology
- Pharmacology (medical)
Cite this
The pharmacologic elegance of inhibiting cholesterol absorption and synthesis while providing a homeostatic balance. / Catapano, Alberico L.
In: Fundamental and Clinical Pharmacology, Vol. 21, No. SUPPL. 2, 11.2007, p. 21-26.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - The pharmacologic elegance of inhibiting cholesterol absorption and synthesis while providing a homeostatic balance
AU - Catapano, Alberico L.
PY - 2007/11
Y1 - 2007/11
N2 - The recent discoveries on the concerted role of several mechanisms involved in regulating the balance of body cholesterol highlight the role of intestinal absorption. Selective modulators of intestinal cholesterol absorption are available that offer a new pharmacologic approach to the modulation of total body cholesterol homeostasis and to a more effective reduction of low-density-lipoprotein cholesterol.
AB - The recent discoveries on the concerted role of several mechanisms involved in regulating the balance of body cholesterol highlight the role of intestinal absorption. Selective modulators of intestinal cholesterol absorption are available that offer a new pharmacologic approach to the modulation of total body cholesterol homeostasis and to a more effective reduction of low-density-lipoprotein cholesterol.
KW - Intestine
KW - LDL
KW - Liver
KW - NPC1L1
UR - http://www.scopus.com/inward/record.url?scp=36248957625&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=36248957625&partnerID=8YFLogxK
U2 - 10.1111/j.1472-8206.2007.00534.x
DO - 10.1111/j.1472-8206.2007.00534.x
M3 - Article
C2 - 18001316
AN - SCOPUS:36248957625
VL - 21
SP - 21
EP - 26
JO - Fundamental and Clinical Pharmacology
JF - Fundamental and Clinical Pharmacology
SN - 0767-3981
IS - SUPPL. 2
ER -