The pivotal role of echocardiography in the assessment of multivalvular heart disease

A. Grimaldi, A. C. Vermi, F. Pappalardo, S. Benussi, A. Fumero, F. Maisano, A. Colombo, G. La Canna, O. Alfieri

Research output: Contribution to journalArticlepeer-review


Multivalvular heart disease (MHD) accounts for approximately 15% of the patients undergoing valve surgery in the EuroHeart Survey and for 8.6% of all valvular surgical interventions. Most clinical studies on valvular heart disease are focused on single-valve disease and very few data stress the difficulties encountered in the diagnostic assessment and clinical decision making of multiple defects, also concerning the reciprocal hemodynamic influence or the overlap of surgical indications. Many fields related to multiple valve disease are not encountered in the European Guidelines on Valvular Heart Disease (ESC) or the American College of Cardiology/American Heart Association (ACC/AHA). Increasing age and new trends of mixed population have newly aroused interest in multivalvular heart disease in the developed countries, still in need of new clinical insights. According to the high comorbidities of candidates, the appropriate diagnostic framework necessary for the correct diagnosis and best clinical outcome may still be challenging. The paper reviews multivalvular heart disease (except congenital heart disease) from aetiology and background definition to surgical outcome, with special emphasis on echocardiographic assessment and clinical interpretation.

Original languageEnglish
Pages (from-to)229-242
Number of pages14
JournalMinerva Cardioangiologica
Issue number2
Publication statusPublished - Apr 2013


  • Cardiac surgical procedures
  • Echocardiography
  • Heart valve disease

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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