The possible clinical predictors of fatigue in parkinson's disease: A study of 135 patients as part of international nonmotor scale validation project

Vinod Metta, Kartik Logishetty, P. Martinez-Martin, Heather M. Gage, P. E S Schartau, T. K. Kaluarachchi, Anne Martin, Per Odin, P. Barone, Fabrizio Stocchi, A. Antonini, K. Ray Chaudhuri

Research output: Contribution to journalArticle

Abstract

Fatigue is a common yet poorly understood and underresearched nonmotor symptom in Parkinson's disease. Although fatigue is recognized to significantly affect health-related quality of life, it remains underrecognised and empirically treated. In this paper, the prevalence of fatigue as measured by a validated visual analogue scale and the Parkinson's disease nonmotor symptoms scale (PDNMSS) was correlated with other motor and nonmotor comorbidities. In a cohort of patients from a range of disease stages, occurrence of fatigue correlated closely with more advanced Parkinson's disease, as well as with depression, anxiety, and sleep disorders, hinting at a common underlying basis.

Original languageEnglish
Article number125271
JournalParkinson's Disease
DOIs
Publication statusPublished - 2011

ASJC Scopus subject areas

  • Neuroscience (miscellaneous)
  • Clinical Neurology
  • Psychiatry and Mental health

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    Metta, V., Logishetty, K., Martinez-Martin, P., Gage, H. M., Schartau, P. E. S., Kaluarachchi, T. K., Martin, A., Odin, P., Barone, P., Stocchi, F., Antonini, A., & Chaudhuri, K. R. (2011). The possible clinical predictors of fatigue in parkinson's disease: A study of 135 patients as part of international nonmotor scale validation project. Parkinson's Disease, [125271]. https://doi.org/10.4061/2011/125271