The possible clinical predictors of fatigue in parkinson's disease: A study of 135 patients as part of international nonmotor scale validation project

Vinod Metta, Kartik Logishetty, P. Martinez-Martin, Heather M. Gage, P. E S Schartau, T. K. Kaluarachchi, Anne Martin, Per Odin, P. Barone, Fabrizio Stocchi, A. Antonini, K. Ray Chaudhuri

Research output: Contribution to journalArticlepeer-review

Abstract

Fatigue is a common yet poorly understood and underresearched nonmotor symptom in Parkinson's disease. Although fatigue is recognized to significantly affect health-related quality of life, it remains underrecognised and empirically treated. In this paper, the prevalence of fatigue as measured by a validated visual analogue scale and the Parkinson's disease nonmotor symptoms scale (PDNMSS) was correlated with other motor and nonmotor comorbidities. In a cohort of patients from a range of disease stages, occurrence of fatigue correlated closely with more advanced Parkinson's disease, as well as with depression, anxiety, and sleep disorders, hinting at a common underlying basis.

Original languageEnglish
Article number125271
JournalParkinson's Disease
DOIs
Publication statusPublished - 2011

ASJC Scopus subject areas

  • Neuroscience (miscellaneous)
  • Clinical Neurology
  • Psychiatry and Mental health

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