Abstract
Objective: Obstetric complications may be an important factor in the development of schizophrenia. The aim of this study is to evaluate the role of these complications in the development of schizophrenia in adult life, with particular attention to the potential role of birth weight. Method: We carried out a case-control study, comprising schizophrenics and patients with diseases of the schizophrenia spectrum as cases, and their healthy male brothers as controls. Obstetric complications were assessed using the "Midwife Protocol" of Parnas et al. Results: The main result was that birth weight may be a risk factor for schizophrenia, as indicated by odds ratio analysis. The confidence intervals are very wide and, without compromising the clinical significance of the results, they give a limited indication of the real entity of the risk. Conclusions: The results contribute to understanding of the role played by a single complications.
| Original language | English |
|---|---|
| Pages (from-to) | 159-161 |
| Number of pages | 3 |
| Journal | Journal of Perinatal Medicine |
| Volume | 35 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - Apr 1 2007 |
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Keywords
- Birth weight
- Fetal growth
- Obstetric complications
- Pregnancy
- Shizophrenia
ASJC Scopus subject areas
- Obstetrics and Gynaecology
- Pediatrics, Perinatology, and Child Health
Cite this
The potential role of high or low birthweight as risk factor for adult schizophrenia. / Bersani, Giuseppe; Manuali, Giorgiana; Ramieri, Luisa; Taddei, Ines; Bersani, Iliana; Conforti, Filippo; Sofia Cattaruzza, Maria; Osborn, John; Pancheri, Paolo.
In: Journal of Perinatal Medicine, Vol. 35, No. 2, 01.04.2007, p. 159-161.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - The potential role of high or low birthweight as risk factor for adult schizophrenia
AU - Bersani, Giuseppe
AU - Manuali, Giorgiana
AU - Ramieri, Luisa
AU - Taddei, Ines
AU - Bersani, Iliana
AU - Conforti, Filippo
AU - Sofia Cattaruzza, Maria
AU - Osborn, John
AU - Pancheri, Paolo
PY - 2007/4/1
Y1 - 2007/4/1
N2 - Objective: Obstetric complications may be an important factor in the development of schizophrenia. The aim of this study is to evaluate the role of these complications in the development of schizophrenia in adult life, with particular attention to the potential role of birth weight. Method: We carried out a case-control study, comprising schizophrenics and patients with diseases of the schizophrenia spectrum as cases, and their healthy male brothers as controls. Obstetric complications were assessed using the "Midwife Protocol" of Parnas et al. Results: The main result was that birth weight may be a risk factor for schizophrenia, as indicated by odds ratio analysis. The confidence intervals are very wide and, without compromising the clinical significance of the results, they give a limited indication of the real entity of the risk. Conclusions: The results contribute to understanding of the role played by a single complications.
AB - Objective: Obstetric complications may be an important factor in the development of schizophrenia. The aim of this study is to evaluate the role of these complications in the development of schizophrenia in adult life, with particular attention to the potential role of birth weight. Method: We carried out a case-control study, comprising schizophrenics and patients with diseases of the schizophrenia spectrum as cases, and their healthy male brothers as controls. Obstetric complications were assessed using the "Midwife Protocol" of Parnas et al. Results: The main result was that birth weight may be a risk factor for schizophrenia, as indicated by odds ratio analysis. The confidence intervals are very wide and, without compromising the clinical significance of the results, they give a limited indication of the real entity of the risk. Conclusions: The results contribute to understanding of the role played by a single complications.
KW - Birth weight
KW - Fetal growth
KW - Obstetric complications
KW - Pregnancy
KW - Shizophrenia
UR - http://www.scopus.com/inward/record.url?scp=33847719969&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33847719969&partnerID=8YFLogxK
U2 - 10.1515/JPM.2007.021
DO - 10.1515/JPM.2007.021
M3 - Article
VL - 35
SP - 159
EP - 161
JO - Journal of Perinatal Medicine
JF - Journal of Perinatal Medicine
SN - 0300-5577
IS - 2
ER -