Abstract
Several kindreds (N,C, To and RB) with familial Alzheimer disease (FAD) from the same small area of Calabria are currently under study. Recently two of us (F.M. and L.F-S.) identified a family in Milan (FJ01) made up of 3 siblings whose parents were of Calabrian origin. Through a subsequent systematic or blanket genealogical study a link has been traced between kindreds To and FJ01. We discuss the relevance of these results to genetic studies.
Original language | English |
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Pages (from-to) | 239-244 |
Number of pages | 6 |
Journal | Italian Journal of Neurological Sciences |
Volume | 14 |
Issue number | 3 |
DOIs | |
Publication status | Published - Apr 1993 |
Keywords
- Familial Alzheimer disease
- founder effect
- genealogical method
ASJC Scopus subject areas
- Neuroscience(all)
- Clinical Neurology