The preparation of leukocyte-poor red cells for transfusion by a simple cost-effective technique

A. Parravicini, P. Rebulla, J. Apuzzo, B. Wenz, G. Sirchia

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

A modification of the microaggregate filtration technique for the production of leukocyte-poor red cell concentrate is described. The modified technique, termed 'spin, cool, and filter', removed leukocytes more efficiently from relatively fresh blood than the original microaggregate filtration procedure. The residual leukocyte content of 4- to 9-day-old units processed by the modified procedure averaged less than 0.4 x 106 white cells per unit. The microaggregate filtration technique, supplemented by buffy-coat exclusion, removed more than 93 percent of the units' white cells. These red cell products were prepared easily and did not elicit febrile reactions in highly susceptible patients.

Original languageEnglish
Pages (from-to)508-509
Number of pages2
JournalTransfusion
Volume24
Issue number6
Publication statusPublished - 1984

Fingerprint

Leukocytes
Costs and Cost Analysis
Fever

ASJC Scopus subject areas

  • Hematology
  • Immunology

Cite this

Parravicini, A., Rebulla, P., Apuzzo, J., Wenz, B., & Sirchia, G. (1984). The preparation of leukocyte-poor red cells for transfusion by a simple cost-effective technique. Transfusion, 24(6), 508-509.

The preparation of leukocyte-poor red cells for transfusion by a simple cost-effective technique. / Parravicini, A.; Rebulla, P.; Apuzzo, J.; Wenz, B.; Sirchia, G.

In: Transfusion, Vol. 24, No. 6, 1984, p. 508-509.

Research output: Contribution to journalArticle

Parravicini, A, Rebulla, P, Apuzzo, J, Wenz, B & Sirchia, G 1984, 'The preparation of leukocyte-poor red cells for transfusion by a simple cost-effective technique', Transfusion, vol. 24, no. 6, pp. 508-509.
Parravicini, A. ; Rebulla, P. ; Apuzzo, J. ; Wenz, B. ; Sirchia, G. / The preparation of leukocyte-poor red cells for transfusion by a simple cost-effective technique. In: Transfusion. 1984 ; Vol. 24, No. 6. pp. 508-509.
@article{20164b364cf046b6a0ece21a6126dce6,
title = "The preparation of leukocyte-poor red cells for transfusion by a simple cost-effective technique",
abstract = "A modification of the microaggregate filtration technique for the production of leukocyte-poor red cell concentrate is described. The modified technique, termed 'spin, cool, and filter', removed leukocytes more efficiently from relatively fresh blood than the original microaggregate filtration procedure. The residual leukocyte content of 4- to 9-day-old units processed by the modified procedure averaged less than 0.4 x 106 white cells per unit. The microaggregate filtration technique, supplemented by buffy-coat exclusion, removed more than 93 percent of the units' white cells. These red cell products were prepared easily and did not elicit febrile reactions in highly susceptible patients.",
author = "A. Parravicini and P. Rebulla and J. Apuzzo and B. Wenz and G. Sirchia",
year = "1984",
language = "English",
volume = "24",
pages = "508--509",
journal = "Transfusion",
issn = "0041-1132",
publisher = "Blackwell Publishing Inc.",
number = "6",

}

TY - JOUR

T1 - The preparation of leukocyte-poor red cells for transfusion by a simple cost-effective technique

AU - Parravicini, A.

AU - Rebulla, P.

AU - Apuzzo, J.

AU - Wenz, B.

AU - Sirchia, G.

PY - 1984

Y1 - 1984

N2 - A modification of the microaggregate filtration technique for the production of leukocyte-poor red cell concentrate is described. The modified technique, termed 'spin, cool, and filter', removed leukocytes more efficiently from relatively fresh blood than the original microaggregate filtration procedure. The residual leukocyte content of 4- to 9-day-old units processed by the modified procedure averaged less than 0.4 x 106 white cells per unit. The microaggregate filtration technique, supplemented by buffy-coat exclusion, removed more than 93 percent of the units' white cells. These red cell products were prepared easily and did not elicit febrile reactions in highly susceptible patients.

AB - A modification of the microaggregate filtration technique for the production of leukocyte-poor red cell concentrate is described. The modified technique, termed 'spin, cool, and filter', removed leukocytes more efficiently from relatively fresh blood than the original microaggregate filtration procedure. The residual leukocyte content of 4- to 9-day-old units processed by the modified procedure averaged less than 0.4 x 106 white cells per unit. The microaggregate filtration technique, supplemented by buffy-coat exclusion, removed more than 93 percent of the units' white cells. These red cell products were prepared easily and did not elicit febrile reactions in highly susceptible patients.

UR - http://www.scopus.com/inward/record.url?scp=0021721892&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0021721892&partnerID=8YFLogxK

M3 - Article

C2 - 6438838

AN - SCOPUS:0021721892

VL - 24

SP - 508

EP - 509

JO - Transfusion

JF - Transfusion

SN - 0041-1132

IS - 6

ER -