TY - JOUR
T1 - The presence of J chain in mesangial immune deposits of IgA nephropathy.
AU - Donini, U.
AU - Casanova, S.
AU - Zini, N.
AU - Zucchelli, P.
PY - 1983
Y1 - 1983
N2 - In order to identify polymeric IgA in the mesangial IgA deposits of 33 patients, the presence of J chains by a PAP method was investigated. In 9/27 cases of primary IgA nephropathy (PIgANP) and in 4/4 cases of Henoch-Schönlein glomerulonephritis (HSGN) J chains were absent. The remaining cases, two of them with IgA glomerulonephritis associated with alcoholic cirrhosis (ACIgAGN), were J-positive. The two groups, PIgANP J-positive and PIgANP J-negative, were compared according to clinical features. The only difference detected was the time length between the disease onset and the renal biopsy, being shorter in the negative group.
AB - In order to identify polymeric IgA in the mesangial IgA deposits of 33 patients, the presence of J chains by a PAP method was investigated. In 9/27 cases of primary IgA nephropathy (PIgANP) and in 4/4 cases of Henoch-Schönlein glomerulonephritis (HSGN) J chains were absent. The remaining cases, two of them with IgA glomerulonephritis associated with alcoholic cirrhosis (ACIgAGN), were J-positive. The two groups, PIgANP J-positive and PIgANP J-negative, were compared according to clinical features. The only difference detected was the time length between the disease onset and the renal biopsy, being shorter in the negative group.
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M3 - Article
C2 - 6410386
AN - SCOPUS:0020654708
VL - 19
SP - 655
EP - 662
JO - Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association
JF - Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association
SN - 0071-2736
ER -