The pressor response after laryngeal mask or cuffed oropharyngeal airway insertion

A. Casati, G. Cappelleri, G. Fanelli, L. Magistris, P. Beccaria, A. Albertin, G. Torri

Research output: Contribution to journalArticlepeer-review


Background: Since the cuffed oropharyngeal airway (COPA) has been suggested to cause less pharyngeal trauma than the laryngeal mask airway (LMA), we conducted a prospective, randomised study to compare haemodynamic changes after placing either the COPA or LMA in healthy anaesthetised adults. Methods: After standard midazolam premedication (0.05 mg kg-1 IV), general anaesthesia (IV propofol 2 mg kg-1) was induced in 60 ASA physical status I-II, 18-65-yr-old patients, who were randomly allocated to receive COPA (n=30) or LMA (n= 30) placement and then mechanically ventilated using a 60% nitrous oxide and 1% isoflurane in oxygen mixture (TV=8 ml kg-1, RR=12 b.p.m., I/E=1/2). Haemodynamic variables were recorded 20 min after the midazolam premedication (baseline), and then every 1 min until 10 min after general anaesthesia induction. Results: Nine patients of group COPA (30%) required chin lift, jaw thrust or head tilt to maintain adequate ventilation, while no problems were observed in the LMA group (P

Original languageEnglish
Pages (from-to)1053-1056
Number of pages4
JournalActa Anaesthesiologica Scandinavica
Issue number10
Publication statusPublished - 1999


  • Airway
  • Anesthesia general
  • Arterial blood pressure
  • Cuffed oropharyngeal airway
  • Hemodynamic effects
  • Isoflurane
  • Laryngeal mask
  • Monitoring

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine


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