The prevalence and clinical relevance of p27 and cyclin E immunoreactivity in myelodysplastic syndromes

Giancarlo Pruneri, Nicola Fracchialla, Agostino Cortelezzi, Maurilio Ponzoni, Patrick Maisonneuve, Giorgio Lambertenghi-Deliliers

Research output: Contribution to journalArticle

Abstract

We report on p27 and cyclin E immunoreactivity (IR) in 86 patients with myelodysplastic syndromes (MDS). No association was found between cyclin E IR and survival in the whole series. Cyclin E IR was more prevalent in patients with refractory anemia (RA) and RA with ringed sideroblasts (RARS) with poor survival, although this trend was not statistically significant.

Original languageEnglish
Pages (from-to)109-110
Number of pages2
JournalHaematologica
Volume88
Issue number1
Publication statusPublished - Feb 1 2003

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Keywords

  • Cyclin E
  • Myelodysplasyic syndromes
  • p27

ASJC Scopus subject areas

  • Hematology

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