The prevalence of antibodies to human herpesvirus 8 and hepatitis B virus in patients in two hospitals in Tanzania

S. Meschi; M. Sañé Schepisi; E. Nicastri; N. Bevilacqua; C. Castilletti; M. R. Sciarrone; M. G. Paglia; R. Fumakule; J. Mohamed; A. Kitwa; S. Mangi; F. Molteni; A. Di Caro; F. Vairo; M. R. Capobianchi; G. Ippolito

doi:10.1002/jmv.21852

The prevalence of antibodies to human herpesvirus 8 and hepatitis B virus in patients in two hospitals in Tanzania

S. Meschi, M. Sañé Schepisi, E. Nicastri, N. Bevilacqua, C. Castilletti, M. R. Sciarrone, M. G. Paglia, R. Fumakule, J. Mohamed, A. Kitwa, S. Mangi, F. Molteni, A. Di Caro, F. Vairo, M. R. Capobianchi, G. Ippolito

Istituto Nazionale per le Malattie Infettive Lazzaro Spallanzani

Research output: Contribution to journal › Article

Abstract

The aim of this study was to determine the seroprevalence of human herpesvirus 8 (HHV-8) and the immunization status for hepatitis B virus (HBV) infection in febrile patients in two districts of the United Republic of Tanzania. Between February and March 2007, blood samples were collected in Pemba Island and Tosamaganga from 336 outpatients and sent to the Virology Laboratory in Rome (Italy) for testing. HHV-8DNA and HBV-DNA were amplified by two in-house molecular methods, anti-HHV-8 antibody titers were determined by an immunofluorescence assay (IFA), and anti-HCV, HBsAg, anti-HBs, and anti-HBc were evaluated by microplate enzyme immunoassay (MEIA). The seroprevalence of HHV-8 was 30.7% (96/313). In Pemba Island, the prevalence was lower than in Tosamaganga (14.4% vs. 46.3%). A higher prevalence of low titers of HHV-8 IgG (

Original language	English
Pages (from-to)	1569-1575
Number of pages	7
Journal	Journal of Medical Virology
Volume	82
Issue number	9
DOIs	https://doi.org/10.1002/jmv.21852
Publication status	Published - Sep 2010

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Keywords

Antibody titer
Hepatitis
Immunization
PCR
Seroprevalence

ASJC Scopus subject areas

Virology
Infectious Diseases

Cite this

Meschi, S., Sañé Schepisi, M., Nicastri, E., Bevilacqua, N., Castilletti, C., Sciarrone, M. R., Paglia, M. G., Fumakule, R., Mohamed, J., Kitwa, A., Mangi, S., Molteni, F., Di Caro, A., Vairo, F., Capobianchi, M. R., & Ippolito, G. (2010). The prevalence of antibodies to human herpesvirus 8 and hepatitis B virus in patients in two hospitals in Tanzania. Journal of Medical Virology, 82(9), 1569-1575. https://doi.org/10.1002/jmv.21852

The prevalence of antibodies to human herpesvirus 8 and hepatitis B virus in patients in two hospitals in Tanzania. / Meschi, S.; Sañé Schepisi, M.; Nicastri, E.; Bevilacqua, N.; Castilletti, C.; Sciarrone, M. R.; Paglia, M. G.; Fumakule, R.; Mohamed, J.; Kitwa, A.; Mangi, S.; Molteni, F.; Di Caro, A.; Vairo, F.; Capobianchi, M. R.; Ippolito, G.

In: Journal of Medical Virology, Vol. 82, No. 9, 09.2010, p. 1569-1575.

Research output: Contribution to journal › Article

Meschi, S , Sañé Schepisi, M , Nicastri, E , Bevilacqua, N , Castilletti, C, Sciarrone, MR, Paglia, MG, Fumakule, R, Mohamed, J, Kitwa, A, Mangi, S, Molteni, F, Di Caro, A , Vairo, F , Capobianchi, MR & Ippolito, G 2010, 'The prevalence of antibodies to human herpesvirus 8 and hepatitis B virus in patients in two hospitals in Tanzania', Journal of Medical Virology, vol. 82, no. 9, pp. 1569-1575. https://doi.org/10.1002/jmv.21852

Meschi, S. ; Sañé Schepisi, M. ; Nicastri, E. ; Bevilacqua, N. ; Castilletti, C. ; Sciarrone, M. R. ; Paglia, M. G. ; Fumakule, R. ; Mohamed, J. ; Kitwa, A. ; Mangi, S. ; Molteni, F. ; Di Caro, A. ; Vairo, F. ; Capobianchi, M. R. ; Ippolito, G. / The prevalence of antibodies to human herpesvirus 8 and hepatitis B virus in patients in two hospitals in Tanzania. In: Journal of Medical Virology. 2010 ; Vol. 82, No. 9. pp. 1569-1575.

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