Prevalenza della sensibilizzazione da contatto ad alcuni coloranti permanenti per capelli

Translated title of the contribution: The prevalence of contact sensitivity to several permanent hair dyes

P. Lisi, K. Hansel, A. Cristaudo, B. Santucci, C. Foti, G. Angelini, R. Valsecchi, R. Gallo, D. Schena, M. Corazza, A. Lodi, P. Danese, G. Gaddoni, S. Francalanci

Research output: Contribution to journalArticlepeer-review


Background: permanent hair dyes are a common cause of allergic contact dermatitis (ACD) in hairdressers and their clients. The sale of these products has progressively decreased in recent years, despite their improved quality and safety. Objectives: the aims of this study were to determine a) the present prevalence of contact sensitivity to p-phenylenediamine (PPD), p-toluenediamine (PTD) and disperse orange 3 (DO3), b) the trend of concomitant or cross reactions to these three dyes, and c) the possible use of PTD and/or DO3 as an alternative to PPD. Materials and methods: 8,573 consecutive patients affected by eczematous dermatitis were patch tested with PTD sulphate, DO3, PPD free base (each 1% in pet.) and the other allergens of the SIDAPA standard series according to the GIRDCA guidelines. The results were statistically analysed. Results and conclusions: allergic reactions to one or more hair dyes were observed in 318 subjects (3.7%). PPD were positive in 307 (3.6%), DO3 in 121 (1.4%) and PTD in 86 (1.1%). Therefore, PPD is still an important contact sensitizer and the best indicator both of allergy to aromatic compounds with an amino group in the para-position and of ACD from hair dye related chemicals. Hair colouring preparations were the most frequent cause of PPD sensitization (199/318), followed by rubber articles (26/318) and textile dyes (19/318). Of the 199 subjects with ACD from hair dyes, 100 (50.3%) showed concomitant positive reactions to PPD, DO3 and/or PTD. Therefore, DO3 and PTD are not alternative to PPD.

Translated title of the contributionThe prevalence of contact sensitivity to several permanent hair dyes
Original languageItalian
Pages (from-to)29-32
Number of pages4
JournalAnnali Italiani di Dermatologia Allergologica Clinica e Sperimentale
Issue number1
Publication statusPublished - 2001

ASJC Scopus subject areas

  • Dermatology


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