The procedure outcome of laparoscopic resection for 'small' hepatocellular carcinoma is comparable to vlaparoscopic radiofrequency ablation

Marco Casaccia, Gregorio Santori, Giuliano Bottino, Pietro Diviacco, Antonella Negri, Eva Moraglia, Enzo Adorno

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Background: The aim of this study was to compare the effectiveness of laparoscopic liver resection (LLR) and laparoscopic radiofrequency ablation (LRFA) in the treatment of small nodular hepatocellular carcinoma (HCC). Patients and Methods: We enrolled 50 cirrhotic patients with similar baseline characteristics that underwent LLR (n = 26) or LRFA (n = 24), in both cases with intraoperative ultrasonography. Operative and peri-operative data were retrospectively evaluated. Results: LLR included anatomic resection in eight cases and non-anatomic resection in 18. In LRFA patients, a thermoablation of 62 nodules was achieved. Between LLR and LRFA groups, a significant difference was found both for median diameters of treated HCC nodules (30 vs. 17.1 mm; P <0.001) and the number of treated nodules/patient (1.29 ± 0.62 vs. 2.65 ± 1.55; P <0.001). A conversion to laparotomy occurred in two LLR patient (7.7%) for bleeding. No deaths occurred in both groups. Morbidity rates were 26.9% in the LLR group versus 16.6% in the LRFA group (P = 0.501). Hospital stay in the LLR and LRFA group was 8.30 ± 6.52 and 6.52 ± 2.69 days, respectively (P = 0.022). The surgical margin was free of tumour cells in all LLR patients, with a margin

Original languageEnglish
Pages (from-to)231-235
Number of pages5
JournalJournal of Minimal Access Surgery
Volume11
Issue number4
DOIs
Publication statusPublished - Oct 1 2015

Fingerprint

Hepatocellular Carcinoma
Liver
Laparotomy
Ultrasonography
Length of Stay
Hemorrhage
Morbidity
Neoplasms

Keywords

  • Hepatocellular carcinoma
  • laparoscopy
  • liver cirrhosis
  • liver resection
  • radiofrequency ablation

ASJC Scopus subject areas

  • Surgery

Cite this

The procedure outcome of laparoscopic resection for 'small' hepatocellular carcinoma is comparable to vlaparoscopic radiofrequency ablation. / Casaccia, Marco; Santori, Gregorio; Bottino, Giuliano; Diviacco, Pietro; Negri, Antonella; Moraglia, Eva; Adorno, Enzo.

In: Journal of Minimal Access Surgery, Vol. 11, No. 4, 01.10.2015, p. 231-235.

Research output: Contribution to journalArticle

Casaccia, Marco ; Santori, Gregorio ; Bottino, Giuliano ; Diviacco, Pietro ; Negri, Antonella ; Moraglia, Eva ; Adorno, Enzo. / The procedure outcome of laparoscopic resection for 'small' hepatocellular carcinoma is comparable to vlaparoscopic radiofrequency ablation. In: Journal of Minimal Access Surgery. 2015 ; Vol. 11, No. 4. pp. 231-235.
@article{75a9b7b234304af9a3e90fec86bd90c8,
title = "The procedure outcome of laparoscopic resection for 'small' hepatocellular carcinoma is comparable to vlaparoscopic radiofrequency ablation",
abstract = "Background: The aim of this study was to compare the effectiveness of laparoscopic liver resection (LLR) and laparoscopic radiofrequency ablation (LRFA) in the treatment of small nodular hepatocellular carcinoma (HCC). Patients and Methods: We enrolled 50 cirrhotic patients with similar baseline characteristics that underwent LLR (n = 26) or LRFA (n = 24), in both cases with intraoperative ultrasonography. Operative and peri-operative data were retrospectively evaluated. Results: LLR included anatomic resection in eight cases and non-anatomic resection in 18. In LRFA patients, a thermoablation of 62 nodules was achieved. Between LLR and LRFA groups, a significant difference was found both for median diameters of treated HCC nodules (30 vs. 17.1 mm; P <0.001) and the number of treated nodules/patient (1.29 ± 0.62 vs. 2.65 ± 1.55; P <0.001). A conversion to laparotomy occurred in two LLR patient (7.7{\%}) for bleeding. No deaths occurred in both groups. Morbidity rates were 26.9{\%} in the LLR group versus 16.6{\%} in the LRFA group (P = 0.501). Hospital stay in the LLR and LRFA group was 8.30 ± 6.52 and 6.52 ± 2.69 days, respectively (P = 0.022). The surgical margin was free of tumour cells in all LLR patients, with a margin",
keywords = "Hepatocellular carcinoma, laparoscopy, liver cirrhosis, liver resection, radiofrequency ablation",
author = "Marco Casaccia and Gregorio Santori and Giuliano Bottino and Pietro Diviacco and Antonella Negri and Eva Moraglia and Enzo Adorno",
year = "2015",
month = "10",
day = "1",
doi = "10.4103/0972-9941.144093",
language = "English",
volume = "11",
pages = "231--235",
journal = "Journal of Minimal Access Surgery",
issn = "0972-9941",
publisher = "Medknow Publications and Media Pvt. Ltd",
number = "4",

}

TY - JOUR

T1 - The procedure outcome of laparoscopic resection for 'small' hepatocellular carcinoma is comparable to vlaparoscopic radiofrequency ablation

AU - Casaccia, Marco

AU - Santori, Gregorio

AU - Bottino, Giuliano

AU - Diviacco, Pietro

AU - Negri, Antonella

AU - Moraglia, Eva

AU - Adorno, Enzo

PY - 2015/10/1

Y1 - 2015/10/1

N2 - Background: The aim of this study was to compare the effectiveness of laparoscopic liver resection (LLR) and laparoscopic radiofrequency ablation (LRFA) in the treatment of small nodular hepatocellular carcinoma (HCC). Patients and Methods: We enrolled 50 cirrhotic patients with similar baseline characteristics that underwent LLR (n = 26) or LRFA (n = 24), in both cases with intraoperative ultrasonography. Operative and peri-operative data were retrospectively evaluated. Results: LLR included anatomic resection in eight cases and non-anatomic resection in 18. In LRFA patients, a thermoablation of 62 nodules was achieved. Between LLR and LRFA groups, a significant difference was found both for median diameters of treated HCC nodules (30 vs. 17.1 mm; P <0.001) and the number of treated nodules/patient (1.29 ± 0.62 vs. 2.65 ± 1.55; P <0.001). A conversion to laparotomy occurred in two LLR patient (7.7%) for bleeding. No deaths occurred in both groups. Morbidity rates were 26.9% in the LLR group versus 16.6% in the LRFA group (P = 0.501). Hospital stay in the LLR and LRFA group was 8.30 ± 6.52 and 6.52 ± 2.69 days, respectively (P = 0.022). The surgical margin was free of tumour cells in all LLR patients, with a margin

AB - Background: The aim of this study was to compare the effectiveness of laparoscopic liver resection (LLR) and laparoscopic radiofrequency ablation (LRFA) in the treatment of small nodular hepatocellular carcinoma (HCC). Patients and Methods: We enrolled 50 cirrhotic patients with similar baseline characteristics that underwent LLR (n = 26) or LRFA (n = 24), in both cases with intraoperative ultrasonography. Operative and peri-operative data were retrospectively evaluated. Results: LLR included anatomic resection in eight cases and non-anatomic resection in 18. In LRFA patients, a thermoablation of 62 nodules was achieved. Between LLR and LRFA groups, a significant difference was found both for median diameters of treated HCC nodules (30 vs. 17.1 mm; P <0.001) and the number of treated nodules/patient (1.29 ± 0.62 vs. 2.65 ± 1.55; P <0.001). A conversion to laparotomy occurred in two LLR patient (7.7%) for bleeding. No deaths occurred in both groups. Morbidity rates were 26.9% in the LLR group versus 16.6% in the LRFA group (P = 0.501). Hospital stay in the LLR and LRFA group was 8.30 ± 6.52 and 6.52 ± 2.69 days, respectively (P = 0.022). The surgical margin was free of tumour cells in all LLR patients, with a margin

KW - Hepatocellular carcinoma

KW - laparoscopy

KW - liver cirrhosis

KW - liver resection

KW - radiofrequency ablation

UR - http://www.scopus.com/inward/record.url?scp=84945174805&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84945174805&partnerID=8YFLogxK

U2 - 10.4103/0972-9941.144093

DO - 10.4103/0972-9941.144093

M3 - Article

AN - SCOPUS:84945174805

VL - 11

SP - 231

EP - 235

JO - Journal of Minimal Access Surgery

JF - Journal of Minimal Access Surgery

SN - 0972-9941

IS - 4

ER -