The prognosis of epilepsy from the time of its diagnosis is extensively reviewed. As most patients (>70%) who experience a second seizure have further seizures, the demonstration of at least two unprovoked seizures is a sufficient neuroepidemiological criterion for the definition of epilepsy. Once the antiepileptic treatment is instituted, the 1-year remission rates in most studies have varied between 65 and 80%. Similarly, long-term remission rates (15 to 20 years from the onset) of treated epilepsy give values around 70%. The prognosis depends on many factors: aetiology, neurological status, number and type of seizures at onset and the epileptic syndrome, the latter being the most important factor. Recent studies trying to address the early prediction of intractable epilepsy demonstrate that patients who have many seizures before therapy or who have an inadequate response to the first monotherapy are likely to have refractory epilepsy. The prognosis of untreated epilepsy is poorly understood, but data obtained from studies in developing countries seem to indicate that a high proportion of patients (50%) may enter spontaneous remission.
|Translated title of the contribution||The prognosis of epilepsy from time of diagnosis|
|Number of pages||4|
|Journal||Bollettino - Lega Italiana contro l'Epilessia|
|Publication status||Published - Jul 2003|
ASJC Scopus subject areas
- Clinical Neurology