The prognostic value of the electroencephalogram in antiepileptic drug withdrawal in partial epilepsies

P. Tinuper, P. Avoni, R. Riva, F. Provini, E. Lugaresi, A. Baruzzi

Research output: Contribution to journalArticle

Abstract

We evaluated the prognostic value of the EEG in 120 seizure-free epileptic patients (49 with complex partial seizures with or without episodic secondarily generalization [CPS], 20 with simple partial seizures with or without episodic secondarily generalization [SPS], 51 with only secondarily generalized seizures [PSG]) during and after antiepileptic drug withdrawal. All patients had EEG examination before; during; and 3, 12, 24, and 36 months after drug withdrawal. Relapse rates were 45% in CPS, 100% in SPS, and 65% in PSG. Before reduction, 36 patients had epileptiform EEG and 69% relapsed; in the group with normal EEG, 60% relapsed. EEG worsened in 36 patients, 83% relapsed, whereas only 54% of patients with unchanged EEG relapsed. EEG during but not at the start of drug withdrawal has a prognostic value in partial epilepsy.

Original languageEnglish
Pages (from-to)76-78
Number of pages3
JournalNeurology
Volume47
Issue number1
Publication statusPublished - Jul 1996

ASJC Scopus subject areas

  • Neuroscience(all)

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