The proper tidal volume target using volume guarantee ventilation in the course of neonatal respiratory distress syndrome: A crucial endpoint

F. Scopesi, F. M. Risso, A. Sannia, C. Traggiai, C. Arioni, E. Zullino, F. Campone, P. Mezzano, D. Massocco, F. Baldi, G. Serra

Research output: Contribution to journalArticle

Abstract

Volume guarantee ventilation (VGV) is an optional ventilation mode which has become the most widely and extensively studied in the last 10 years in premature infants. Nonetheless, theoretical expected endpoints are intriguing and even though VGV has not yet become 'the' standard ventilation mode, a great deal of information has been acquired and stored. In our experience, VGV during the course of respiratory distress syndrome is useful and can be considered a standard ventilation mode. Weaning occurs in real time as described earlier, and synchronized intermittent positive pressure ventilation and pressure support ventilation (PSV) seem to be the preferred combined modes. Management during the acute phase requires more care since several sudden changes take place in both the lung mechanics and clinical behavior. The software is designed to protect the lung, and subsequently, sudden changes in lung compliance following iatrogenic procedures such as surfactant administration are powerfully counteracted. VGV has been extensively studied and the proposed algorithm has been found to function as planned. Although the 'superiority' of one method over another cannot be demonstrated, the use of new technologies require 'a staff learning curve' and homogeneity of treatment, while at the same time other factors, such as patient heterogeneity or illness phase, should be taken into due account.

Original languageEnglish
Pages (from-to)692-694
Number of pages3
JournalJournal of Maternal-Fetal and Neonatal Medicine
Volume23
Issue number7
DOIs
Publication statusPublished - 2010

Keywords

  • Newborn
  • Tidal volume
  • Volume guarantee ventilation

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynaecology
  • Medicine(all)

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    Scopesi, F., Risso, F. M., Sannia, A., Traggiai, C., Arioni, C., Zullino, E., Campone, F., Mezzano, P., Massocco, D., Baldi, F., & Serra, G. (2010). The proper tidal volume target using volume guarantee ventilation in the course of neonatal respiratory distress syndrome: A crucial endpoint. Journal of Maternal-Fetal and Neonatal Medicine, 23(7), 692-694. https://doi.org/10.3109/14767050903440448