The prospective white matter: An atypical neurogenic niche in the developing cerebellum

K. Leto, A. Bartolini, F. Rossi

Research output: Contribution to journalArticle

Abstract

Cerebellar GABAergic interneurons comprise heterogeneous phenotypes located at strategic levels of the local networks. Recent findings indicate that they all derive from a common population of multipotent progenitors whose fate choices are determined by instructive information provided by the PWM environment. Here we review about the atypical neurogenic strategy operated within such postnatal niche and we discuss possible instructive mechanisms governing interneuron specification and differentiation.

Original languageEnglish
Pages (from-to)137-146
Number of pages10
JournalArchives Italiennes de Biologie
Volume148
Issue number2
Publication statusPublished - 2010

Keywords

  • Cell specification
  • Cerebellum
  • GABAergic interneuron
  • Neural development
  • Postnatal niche

ASJC Scopus subject areas

  • Medicine(all)
  • Cell Biology
  • Physiology

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