The putative role of neuronal network synchronization as a potential biomarker for bipolar disorder: A review of EEG studies

E. Maggioni, A. M. Bianchi, A. C. Altamura, Jair C. Soares, P. Brambilla

Research output: Contribution to journalReview article

Abstract

Impaired intra-hemispheric and inter-hemispheric communication play a major role in the pathophysiology and cognitive disturbances of bipolar disorder (BD). Brain connectivity in BD has been largely investigated using magnetic resonance imaging (MRI) techniques, which have found alterations in prefronto-limbic coupling. In contrast, evidence for functional neural circuitry abnormalities in BD is less consistent. Indeed, just a few studies employing the electroencephalographic (EEG) technique, enabling the exploration of oscillatory brain dynamics, addressed this issue. Therefore, in the present review we summarize the results from EEG studies examining connectivity in patients with BD, to further clarify the putative role of neuronal network synchronization as a potential biomarker of this disabling mental illness.

Original languageEnglish
Pages (from-to)167-170
Number of pages4
JournalJournal of Affective Disorders
Volume212
DOIs
Publication statusPublished - Apr 1 2017

Keywords

  • Bipolar disorder
  • Connectivity
  • EEG

ASJC Scopus subject areas

  • Clinical Psychology
  • Psychiatry and Mental health

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