The relation between multiple pains and mental disorders: Results from the World Mental Health Surveys

Oye Gureje, Michael Von Korff, Lola Kola, Koen Demyttenaere, Yanling He, José Posada-Villa, Jean Pierre Lepine, Matthias C. Angermeyer, Daphna Levinson, Giovanni de Girolamo, Noboru Iwata, Aimee Karam, Guilherme Luiz Guimaraes Borges, Ron de Graaf, Mark Oakley Browne, Dan J. Stein, Josep Maria Haro, Evelyn J. Bromet, Ron C. Kessler, Jordi Alonso

Research output: Contribution to journalArticlepeer-review

Abstract

It is unclear whether differences exist in the prevalence of mood, anxiety and alcohol use disorders among persons with multiple pain conditions compared with those with single pain problems. We conducted population surveys in 17 countries in Europe, the Americas, the Middle East, Africa, Asia, and the South Pacific. Participants were community-dwelling adults (N = 85,088). Mental disorders were assessed with the Composite International Diagnostic Interview. Pain was assessed by self-report. Both multiple and single site pain problems were associated with mood and anxiety disorders, but not with alcohol abuse or dependence. In general, the prevalence of specific mood and anxiety disorders followed a linear pattern with the lowest rates found among persons with no pain, intermediate rates among those with one pain, and highest rates among those with multi-site pain problems. Relative to persons not reporting pain, the pooled estimates of the age-sex adjusted odds ratios were 1.8 (1.7-2.0) for mood disorders and 1.9 (1.8-2.1) for anxiety disorders for persons with single site pain; 3.7 (3.3-4.1) for mood disorders and 3.6 (3.3-4.0) for anxiety disorders among those with multi-site pain. Our results indicate that the presence of multiple pain conditions was strongly and comparably associated with mood and anxiety disorders in diverse cultures. This consistent pattern of associations suggests that diffuse pain and psychiatric disorders are generally associated, rather than diffuse pain representing an idiom for expressing distress that is specific to particular cultural settings or diffuse pain solely representing a form of masked depression.

Original languageEnglish
Pages (from-to)82-91
Number of pages10
JournalPain
Volume135
Issue number1-2
DOIs
Publication statusPublished - Mar 2008

Keywords

  • Alcohol abuse
  • Anxiety
  • Cross national
  • Depression
  • Multiple pains

ASJC Scopus subject areas

  • Clinical Neurology
  • Psychiatry and Mental health
  • Neurology
  • Neuroscience(all)
  • Pharmacology
  • Clinical Psychology

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