The relationship between allergy, clinical symptoms and bronchial responsiveness in atopic dermatitis

G. Fabrizi, G. M. Corbo, E. Ferrante, B. Macciocchi, V. De Angelis, A. Romano, N. Agabiti, E. G. De Vicuna, P. Vultaggio, E. Angelini, S. Valente, G. Ciappi

Research output: Contribution to journalArticlepeer-review

Abstract

Atopic Dermatitis (AD) and asthma are closely associated with respect to epidemiology, hereditary factors and occurrence in the same individuals. Bronchial Hyperresponsiveness (BH), the hallmark of asthma, can also be a physiopathological feature of AD, even in the absence of clinical asthma. We studied 78 subjects with AD. A follow-up study was performed in 27 of these. Data on respiratory and dermatologic symptoms were collected by means of a standardized questionnaire. Skin reactivity was evaluated by prick testing, and in 57 subjects BH was assessed with a methacholine test (Mch). Twenty-one subjects had asthma and 36 showed a positive skin reaction. A PC20 FEV1 was measurable in 38 subjects. Males were found more likely to be Mch responders than females (p

Original languageEnglish
Pages (from-to)68-73
Number of pages6
JournalActa Dermato-Venereologica, Supplement
Issue number176
Publication statusPublished - 1992

Keywords

  • Atopic dermatitis
  • Bronchial asthma
  • Bronchial hyperresponsiveness

ASJC Scopus subject areas

  • Dermatology

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