The relationship of urethral resistance pressure and pressure flow parameters in women with lower urinary tract symptoms

G. Alessandro Digesu, Charlotte Chaliha, Vik Khullar, Stefano Salvatore, Rodolfo Milani, Cinzia Cacciapuoti, Stavros Athanasiou

Research output: Contribution to journalArticlepeer-review

Abstract

This prospective study aims to evaluate the relationship between urethral resistance pressure (URP) and pressure flow parameters in women with lower urinary tract symptoms (LUTS). Consecutive women with LUTS attending three tertiary referral urodynamic clinics were asked to undergo urodynamic evaluation, pressure flow studies and URP measurement. The pressure flow parameters such as detrusor pressures at the start of flow (ODP), detrusor pressure at peak flow rate (PdetQmax), peak flow rate (Qmax) and detrusor pressure at the end of flow (CDP) were measured. The relationship between URP and pressure flow parameters was evaluated as well as differences between each urodynamic group. Two hundred seventy-nine women attended for urodynamic investigations. Two hundred twenty-three (79.9%) women had good quality pressure flow measurements and were included in the study. The mean age was 58 years (range 21-83). Women with urodynamic stress incontinence had significantly lower URP and ODP than those with detrusor over-activity [54.8 (±17.9) and 12.4 (±4.1) cmH2O, respectively, vs 85.6 (±21.4) and 33.7 (±13.3) cmH2O, respectively) (p

Original languageEnglish
Pages (from-to)493-497
Number of pages5
JournalInternational Urogynecology Journal and Pelvic Floor Dysfunction
Volume18
Issue number5
DOIs
Publication statusPublished - May 2007

Keywords

  • Lower urinary tract symptoms
  • Pressure flow study
  • Urethral outlet resistance
  • Urethral resistance pressure
  • Urinary incontinence
  • Uro dynamics

ASJC Scopus subject areas

  • Urology
  • Obstetrics and Gynaecology

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