The ratio between Y chromosome length and the mean length of the four F chromosomes was estimated in 44 patients with cryptorchidism. The mean (1,1007 ± 0,1148) was significantly higher than normal, though no difference could be detected between unilateral and bilateral forms. The ratio between the fluorescent part and the total length of the Y chromosome was also calculated and compared with the Y/F ratio for each case. A significant correlation was evident only in subjects with bilateral cryptorchidism. The significance of these findings is discussed in the light of present knowledge concerning the site and pathology of the genes responsible for sexual differentiation and maturation.
|Translated title of the contribution||The relationships between cryptorchidism and 'long' Y chromosome|
|Number of pages||6|
|Publication status||Published - 1977|
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health