The (r)evolution of cancer genetics

Francesca D. Ciccarelli

doi:10.1186/1741-7007-8-74

The (r)evolution of cancer genetics

Francesca D. Ciccarelli

Istituto Europeo di Oncologia

Research output: Contribution to journal › Article

Abstract

The identification of an increasing number of cancer genes is opening up unexpected scenarios in cancer genetics. When analyzed for their systemic properties, these genes show a general fragility towards perturbation. A recent paper published in BMC Biology shows how the founder domains of known cancer genes emerged at two macroevolutionary transitions - the advent of the first cell and the transition to metazoan multicellularity.

Original language	English
Article number	74
Journal	BMC Biology
Volume	8
DOIs	https://doi.org/10.1186/1741-7007-8-74
Publication status	Published - May 11 2010

ASJC Scopus subject areas

Physiology
Biotechnology
Structural Biology
Developmental Biology
Plant Science
Ecology, Evolution, Behavior and Systematics
Cell Biology
Biochemistry, Genetics and Molecular Biology(all)
Agricultural and Biological Sciences(all)

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Ciccarelli, F. D. (2010). The (r)evolution of cancer genetics. BMC Biology, 8, [74]. https://doi.org/10.1186/1741-7007-8-74

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