Abstract
The identification of an increasing number of cancer genes is opening up unexpected scenarios in cancer genetics. When analyzed for their systemic properties, these genes show a general fragility towards perturbation. A recent paper published in BMC Biology shows how the founder domains of known cancer genes emerged at two macroevolutionary transitions - the advent of the first cell and the transition to metazoan multicellularity.
Original language | English |
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Article number | 74 |
Journal | BMC Biology |
Volume | 8 |
DOIs | |
Publication status | Published - May 11 2010 |
ASJC Scopus subject areas
- Physiology
- Biotechnology
- Structural Biology
- Developmental Biology
- Plant Science
- Ecology, Evolution, Behavior and Systematics
- Cell Biology
- Biochemistry, Genetics and Molecular Biology(all)
- Agricultural and Biological Sciences(all)