The risk profile for obstructive sleep apnea does not affect the recurrence of atrial fibrillation

Luigi Padeletti, Gian Franco Gensini, Paolo Pieragnoli, Pierantonio Ravazzi, Paolo Diotallevi, Nicola Baldi, Vitantonio Russo, Serafino Orazi, Eraldo Occhetta, Margherita Padeletti, Giorgio Corbucci, Sanja Jelic, S. Serge Barold

Research output: Contribution to journalArticle

Abstract

Background: Obstructive sleep apnea (OSA) has been linked to increased prevalence and recurrence of atrial fibrillation (AF). We hypothesized that OSA may aggravate AF in patients with pacemakers implanted for sinus bradycardia who had documented paroxysmal AF. Methods: Seventy-two patients (36 M, aged 77 ± 6 years) completed the study. All patients received a dual-chamber pacemaker equipped with diagnostic and preventive functions for AF. OSA was diagnosed with the Berlin Questionnaire, which is validated to identify patients with OSA. Four-month continuous pacemaker recordings were collected for all patients. Results: OSA was diagnosed in 28% of patients. Patients at high risk for OSA (HR group) and patients at low risk for OSA (LR group) were equivalent for gender, age, and body mass index. The rate of hypertension was higher in HR than in LR group (90% vs 44%, P <0.01). The prevalence of paroxysmal AF during the study period was similar in HR and LR group (53% vs 44%, P = NS). Overall number of AF episodes per month was not significantly different between HR and LR group (7 ± 13 vs 36 ± 122, P = NS). Similarly, AF burden (AF%) was not significantly different between HR and LR group (0.3 ± 0.6 vs 2.0 ± 4.8, P = NS). Circadian distribution of AF episodes was similar in both groups. Conclusion: Long-term pacemaker recording of AF recurrence, AF burden, and its circadian distribution is similar in patients with paroxysmal AF at high risk for OSA and those at low risk for OSA.

Original languageEnglish
Pages (from-to)727-732
Number of pages6
JournalPACE - Pacing and Clinical Electrophysiology
Volume29
Issue number7
DOIs
Publication statusPublished - Jul 2006

Fingerprint

Obstructive Sleep Apnea
Atrial Fibrillation
Recurrence
Berlin
Bradycardia
Body Mass Index
Hypertension

Keywords

  • Atrial fibrillation
  • Pacemaker
  • Sinus bradycardia
  • Sleep apnea

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Padeletti, L., Gensini, G. F., Pieragnoli, P., Ravazzi, P., Diotallevi, P., Baldi, N., ... Barold, S. S. (2006). The risk profile for obstructive sleep apnea does not affect the recurrence of atrial fibrillation. PACE - Pacing and Clinical Electrophysiology, 29(7), 727-732. https://doi.org/10.1111/j.1540-8159.2006.00426.x

The risk profile for obstructive sleep apnea does not affect the recurrence of atrial fibrillation. / Padeletti, Luigi; Gensini, Gian Franco; Pieragnoli, Paolo; Ravazzi, Pierantonio; Diotallevi, Paolo; Baldi, Nicola; Russo, Vitantonio; Orazi, Serafino; Occhetta, Eraldo; Padeletti, Margherita; Corbucci, Giorgio; Jelic, Sanja; Barold, S. Serge.

In: PACE - Pacing and Clinical Electrophysiology, Vol. 29, No. 7, 07.2006, p. 727-732.

Research output: Contribution to journalArticle

Padeletti, L, Gensini, GF, Pieragnoli, P, Ravazzi, P, Diotallevi, P, Baldi, N, Russo, V, Orazi, S, Occhetta, E, Padeletti, M, Corbucci, G, Jelic, S & Barold, SS 2006, 'The risk profile for obstructive sleep apnea does not affect the recurrence of atrial fibrillation', PACE - Pacing and Clinical Electrophysiology, vol. 29, no. 7, pp. 727-732. https://doi.org/10.1111/j.1540-8159.2006.00426.x
Padeletti, Luigi ; Gensini, Gian Franco ; Pieragnoli, Paolo ; Ravazzi, Pierantonio ; Diotallevi, Paolo ; Baldi, Nicola ; Russo, Vitantonio ; Orazi, Serafino ; Occhetta, Eraldo ; Padeletti, Margherita ; Corbucci, Giorgio ; Jelic, Sanja ; Barold, S. Serge. / The risk profile for obstructive sleep apnea does not affect the recurrence of atrial fibrillation. In: PACE - Pacing and Clinical Electrophysiology. 2006 ; Vol. 29, No. 7. pp. 727-732.
@article{fa9308bd4fe74fa2806e2528f0d03118,
title = "The risk profile for obstructive sleep apnea does not affect the recurrence of atrial fibrillation",
abstract = "Background: Obstructive sleep apnea (OSA) has been linked to increased prevalence and recurrence of atrial fibrillation (AF). We hypothesized that OSA may aggravate AF in patients with pacemakers implanted for sinus bradycardia who had documented paroxysmal AF. Methods: Seventy-two patients (36 M, aged 77 ± 6 years) completed the study. All patients received a dual-chamber pacemaker equipped with diagnostic and preventive functions for AF. OSA was diagnosed with the Berlin Questionnaire, which is validated to identify patients with OSA. Four-month continuous pacemaker recordings were collected for all patients. Results: OSA was diagnosed in 28{\%} of patients. Patients at high risk for OSA (HR group) and patients at low risk for OSA (LR group) were equivalent for gender, age, and body mass index. The rate of hypertension was higher in HR than in LR group (90{\%} vs 44{\%}, P <0.01). The prevalence of paroxysmal AF during the study period was similar in HR and LR group (53{\%} vs 44{\%}, P = NS). Overall number of AF episodes per month was not significantly different between HR and LR group (7 ± 13 vs 36 ± 122, P = NS). Similarly, AF burden (AF{\%}) was not significantly different between HR and LR group (0.3 ± 0.6 vs 2.0 ± 4.8, P = NS). Circadian distribution of AF episodes was similar in both groups. Conclusion: Long-term pacemaker recording of AF recurrence, AF burden, and its circadian distribution is similar in patients with paroxysmal AF at high risk for OSA and those at low risk for OSA.",
keywords = "Atrial fibrillation, Pacemaker, Sinus bradycardia, Sleep apnea",
author = "Luigi Padeletti and Gensini, {Gian Franco} and Paolo Pieragnoli and Pierantonio Ravazzi and Paolo Diotallevi and Nicola Baldi and Vitantonio Russo and Serafino Orazi and Eraldo Occhetta and Margherita Padeletti and Giorgio Corbucci and Sanja Jelic and Barold, {S. Serge}",
year = "2006",
month = "7",
doi = "10.1111/j.1540-8159.2006.00426.x",
language = "English",
volume = "29",
pages = "727--732",
journal = "PACE - Pacing and Clinical Electrophysiology",
issn = "0147-8389",
publisher = "Wiley-Blackwell",
number = "7",

}

TY - JOUR

T1 - The risk profile for obstructive sleep apnea does not affect the recurrence of atrial fibrillation

AU - Padeletti, Luigi

AU - Gensini, Gian Franco

AU - Pieragnoli, Paolo

AU - Ravazzi, Pierantonio

AU - Diotallevi, Paolo

AU - Baldi, Nicola

AU - Russo, Vitantonio

AU - Orazi, Serafino

AU - Occhetta, Eraldo

AU - Padeletti, Margherita

AU - Corbucci, Giorgio

AU - Jelic, Sanja

AU - Barold, S. Serge

PY - 2006/7

Y1 - 2006/7

N2 - Background: Obstructive sleep apnea (OSA) has been linked to increased prevalence and recurrence of atrial fibrillation (AF). We hypothesized that OSA may aggravate AF in patients with pacemakers implanted for sinus bradycardia who had documented paroxysmal AF. Methods: Seventy-two patients (36 M, aged 77 ± 6 years) completed the study. All patients received a dual-chamber pacemaker equipped with diagnostic and preventive functions for AF. OSA was diagnosed with the Berlin Questionnaire, which is validated to identify patients with OSA. Four-month continuous pacemaker recordings were collected for all patients. Results: OSA was diagnosed in 28% of patients. Patients at high risk for OSA (HR group) and patients at low risk for OSA (LR group) were equivalent for gender, age, and body mass index. The rate of hypertension was higher in HR than in LR group (90% vs 44%, P <0.01). The prevalence of paroxysmal AF during the study period was similar in HR and LR group (53% vs 44%, P = NS). Overall number of AF episodes per month was not significantly different between HR and LR group (7 ± 13 vs 36 ± 122, P = NS). Similarly, AF burden (AF%) was not significantly different between HR and LR group (0.3 ± 0.6 vs 2.0 ± 4.8, P = NS). Circadian distribution of AF episodes was similar in both groups. Conclusion: Long-term pacemaker recording of AF recurrence, AF burden, and its circadian distribution is similar in patients with paroxysmal AF at high risk for OSA and those at low risk for OSA.

AB - Background: Obstructive sleep apnea (OSA) has been linked to increased prevalence and recurrence of atrial fibrillation (AF). We hypothesized that OSA may aggravate AF in patients with pacemakers implanted for sinus bradycardia who had documented paroxysmal AF. Methods: Seventy-two patients (36 M, aged 77 ± 6 years) completed the study. All patients received a dual-chamber pacemaker equipped with diagnostic and preventive functions for AF. OSA was diagnosed with the Berlin Questionnaire, which is validated to identify patients with OSA. Four-month continuous pacemaker recordings were collected for all patients. Results: OSA was diagnosed in 28% of patients. Patients at high risk for OSA (HR group) and patients at low risk for OSA (LR group) were equivalent for gender, age, and body mass index. The rate of hypertension was higher in HR than in LR group (90% vs 44%, P <0.01). The prevalence of paroxysmal AF during the study period was similar in HR and LR group (53% vs 44%, P = NS). Overall number of AF episodes per month was not significantly different between HR and LR group (7 ± 13 vs 36 ± 122, P = NS). Similarly, AF burden (AF%) was not significantly different between HR and LR group (0.3 ± 0.6 vs 2.0 ± 4.8, P = NS). Circadian distribution of AF episodes was similar in both groups. Conclusion: Long-term pacemaker recording of AF recurrence, AF burden, and its circadian distribution is similar in patients with paroxysmal AF at high risk for OSA and those at low risk for OSA.

KW - Atrial fibrillation

KW - Pacemaker

KW - Sinus bradycardia

KW - Sleep apnea

UR - http://www.scopus.com/inward/record.url?scp=33745958450&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33745958450&partnerID=8YFLogxK

U2 - 10.1111/j.1540-8159.2006.00426.x

DO - 10.1111/j.1540-8159.2006.00426.x

M3 - Article

C2 - 16884508

AN - SCOPUS:33745958450

VL - 29

SP - 727

EP - 732

JO - PACE - Pacing and Clinical Electrophysiology

JF - PACE - Pacing and Clinical Electrophysiology

SN - 0147-8389

IS - 7

ER -