Abstract
Background: Obstructive sleep apnea (OSA) has been linked to increased prevalence and recurrence of atrial fibrillation (AF). We hypothesized that OSA may aggravate AF in patients with pacemakers implanted for sinus bradycardia who had documented paroxysmal AF. Methods: Seventy-two patients (36 M, aged 77 ± 6 years) completed the study. All patients received a dual-chamber pacemaker equipped with diagnostic and preventive functions for AF. OSA was diagnosed with the Berlin Questionnaire, which is validated to identify patients with OSA. Four-month continuous pacemaker recordings were collected for all patients. Results: OSA was diagnosed in 28% of patients. Patients at high risk for OSA (HR group) and patients at low risk for OSA (LR group) were equivalent for gender, age, and body mass index. The rate of hypertension was higher in HR than in LR group (90% vs 44%, P <0.01). The prevalence of paroxysmal AF during the study period was similar in HR and LR group (53% vs 44%, P = NS). Overall number of AF episodes per month was not significantly different between HR and LR group (7 ± 13 vs 36 ± 122, P = NS). Similarly, AF burden (AF%) was not significantly different between HR and LR group (0.3 ± 0.6 vs 2.0 ± 4.8, P = NS). Circadian distribution of AF episodes was similar in both groups. Conclusion: Long-term pacemaker recording of AF recurrence, AF burden, and its circadian distribution is similar in patients with paroxysmal AF at high risk for OSA and those at low risk for OSA.
| Original language | English |
|---|---|
| Pages (from-to) | 727-732 |
| Number of pages | 6 |
| Journal | PACE - Pacing and Clinical Electrophysiology |
| Volume | 29 |
| Issue number | 7 |
| DOIs | |
| Publication status | Published - Jul 2006 |
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Keywords
- Atrial fibrillation
- Pacemaker
- Sinus bradycardia
- Sleep apnea
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
Cite this
The risk profile for obstructive sleep apnea does not affect the recurrence of atrial fibrillation. / Padeletti, Luigi; Gensini, Gian Franco; Pieragnoli, Paolo; Ravazzi, Pierantonio; Diotallevi, Paolo; Baldi, Nicola; Russo, Vitantonio; Orazi, Serafino; Occhetta, Eraldo; Padeletti, Margherita; Corbucci, Giorgio; Jelic, Sanja; Barold, S. Serge.
In: PACE - Pacing and Clinical Electrophysiology, Vol. 29, No. 7, 07.2006, p. 727-732.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - The risk profile for obstructive sleep apnea does not affect the recurrence of atrial fibrillation
AU - Padeletti, Luigi
AU - Gensini, Gian Franco
AU - Pieragnoli, Paolo
AU - Ravazzi, Pierantonio
AU - Diotallevi, Paolo
AU - Baldi, Nicola
AU - Russo, Vitantonio
AU - Orazi, Serafino
AU - Occhetta, Eraldo
AU - Padeletti, Margherita
AU - Corbucci, Giorgio
AU - Jelic, Sanja
AU - Barold, S. Serge
PY - 2006/7
Y1 - 2006/7
N2 - Background: Obstructive sleep apnea (OSA) has been linked to increased prevalence and recurrence of atrial fibrillation (AF). We hypothesized that OSA may aggravate AF in patients with pacemakers implanted for sinus bradycardia who had documented paroxysmal AF. Methods: Seventy-two patients (36 M, aged 77 ± 6 years) completed the study. All patients received a dual-chamber pacemaker equipped with diagnostic and preventive functions for AF. OSA was diagnosed with the Berlin Questionnaire, which is validated to identify patients with OSA. Four-month continuous pacemaker recordings were collected for all patients. Results: OSA was diagnosed in 28% of patients. Patients at high risk for OSA (HR group) and patients at low risk for OSA (LR group) were equivalent for gender, age, and body mass index. The rate of hypertension was higher in HR than in LR group (90% vs 44%, P <0.01). The prevalence of paroxysmal AF during the study period was similar in HR and LR group (53% vs 44%, P = NS). Overall number of AF episodes per month was not significantly different between HR and LR group (7 ± 13 vs 36 ± 122, P = NS). Similarly, AF burden (AF%) was not significantly different between HR and LR group (0.3 ± 0.6 vs 2.0 ± 4.8, P = NS). Circadian distribution of AF episodes was similar in both groups. Conclusion: Long-term pacemaker recording of AF recurrence, AF burden, and its circadian distribution is similar in patients with paroxysmal AF at high risk for OSA and those at low risk for OSA.
AB - Background: Obstructive sleep apnea (OSA) has been linked to increased prevalence and recurrence of atrial fibrillation (AF). We hypothesized that OSA may aggravate AF in patients with pacemakers implanted for sinus bradycardia who had documented paroxysmal AF. Methods: Seventy-two patients (36 M, aged 77 ± 6 years) completed the study. All patients received a dual-chamber pacemaker equipped with diagnostic and preventive functions for AF. OSA was diagnosed with the Berlin Questionnaire, which is validated to identify patients with OSA. Four-month continuous pacemaker recordings were collected for all patients. Results: OSA was diagnosed in 28% of patients. Patients at high risk for OSA (HR group) and patients at low risk for OSA (LR group) were equivalent for gender, age, and body mass index. The rate of hypertension was higher in HR than in LR group (90% vs 44%, P <0.01). The prevalence of paroxysmal AF during the study period was similar in HR and LR group (53% vs 44%, P = NS). Overall number of AF episodes per month was not significantly different between HR and LR group (7 ± 13 vs 36 ± 122, P = NS). Similarly, AF burden (AF%) was not significantly different between HR and LR group (0.3 ± 0.6 vs 2.0 ± 4.8, P = NS). Circadian distribution of AF episodes was similar in both groups. Conclusion: Long-term pacemaker recording of AF recurrence, AF burden, and its circadian distribution is similar in patients with paroxysmal AF at high risk for OSA and those at low risk for OSA.
KW - Atrial fibrillation
KW - Pacemaker
KW - Sinus bradycardia
KW - Sleep apnea
UR - http://www.scopus.com/inward/record.url?scp=33745958450&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33745958450&partnerID=8YFLogxK
U2 - 10.1111/j.1540-8159.2006.00426.x
DO - 10.1111/j.1540-8159.2006.00426.x
M3 - Article
C2 - 16884508
AN - SCOPUS:33745958450
VL - 29
SP - 727
EP - 732
JO - PACE - Pacing and Clinical Electrophysiology
JF - PACE - Pacing and Clinical Electrophysiology
SN - 0147-8389
IS - 7
ER -