The role of a Mediterranean diet on the risk of oral and pharyngeal cancer

M. Filomeno, C. Bosetti, W. Garavello, F. Levi, C. Galeone, E. Negri, C. La Vecchia

Research output: Contribution to journalArticlepeer-review

Abstract

Background: The Mediterranean diet has a beneficial role on various neoplasms, but data are scanty on oral cavity and pharyngeal (OCP) cancer. Methods: We analysed data from a case-control study carried out between 1997 and 2009 in Italy and Switzerland, including 768 incident, histologically confirmed OCP cancer cases and 2078 hospital controls. Adherence to the Mediterranean diet was measured using the Mediterranean Diet Score (MDS) based on the major characteristics of the Mediterranean diet, and two other scores, the Mediterranean Dietary Pattern Adherence Index (MDP) and the Mediterranean Adequacy Index (MAI). Results: We estimated the odds ratios (ORs), and the corresponding 95% confidence intervals (CI), for increasing levels of the scores (i.e., increasing adherence) using multiple logistic regression models. We found a reduced risk of OCP cancer for increasing levels of the MDS, the ORs for subjects with six or more MDS components compared with two or less being 0.20 (95% CI 0.14-0.28, P-value for trend

Original languageEnglish
Pages (from-to)981-986
Number of pages6
JournalBritish Journal of Cancer
Volume111
Issue number5
DOIs
Publication statusPublished - 2014

Keywords

  • case-control
  • Mediterranean diet
  • oral cancer
  • pharyngeal cancer
  • risk factor

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

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