The role of a post therapeutic surveillance program for sinonasal malignancies: Analysis of 417 patients

Jacopo Zocchi, Giacomo Pietrobon, Isotta Campomagnani, Emilia Riggi, Giovanni Veronesi, Rossana Borchini, Raul Pellini, Luca Volpi, Maurizio Bignami, Paolo Castelnuovo

Research output: Contribution to journalArticlepeer-review


Background: Post therapeutic surveillance of head and neck neoplasms is a still debated issue in the current literature: although different works tried to establish frequency, modality, and efficacy of a routine follow-up, little evidence has been produced, in particular considering only sinonasal malignancies. Methods: A retrospective review of patients treated for sinonasal malignancies in a single tertiary center and followed through a regular program of follow-up was carried out. Rate of recurrence, location, timing, diagnosis, and salvage treatment were the main data analyzed. Results: Of note, 417 patients were included in the study and 117 experienced at least one relapse. Staging, histological type, and previous treatment represent the main clinical factors to be considered to stratify patient's risk of recurrence. Conclusion: A regular post therapeutic surveillance can provide an early recurrence detection for patients treated for sinonasal malignancies, offering opportunity for salvage treatment in a high percentage of patients.

Original languageEnglish
JournalHead and Neck
Publication statusAccepted/In press - Jan 1 2019


  • endoscopic sinus surgery
  • oncology
  • sinonasal malignancies
  • skull base
  • surveillance

ASJC Scopus subject areas

  • Otorhinolaryngology


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