Ruolo degli inibitori dell'angiotensina II nell'ipertensione arteriosa: Trial clinici e linee guida

Translated title of the contribution: The role of angiotensin II inhibitors in hypertension: Clinical trials and guidelines

G. Mancia, G. Grassi

Research output: Contribution to journalArticlepeer-review

Abstract

Despite many outstanding favorable results obtained over the past 30-40 years in the treatment of hypertension, several goals of antihypertensive therapy remain unmet. One of them concerns the epidemiological evidence that only 25% of treated hypertensive patients have optimal blood pressure control. Clinical use of new antihypertensive drugs is aimed at achieving the above-mentioned goals, and in particular, at providing more effective blood pressure control, greater cardiovascular protection, and better patient compliance to antihypertensive drug treatment. This paper will examine the main clinical features of angiotensin II receptor blockers, highlighting the results of clinical studies performed thus far, and the main goals of ongoing clinical trials with these drugs. Finally, the role of these compounds in the therapeutic approach to the hypertensive state according to the recent guidelines of the World Health Organization/International Society of Hypertension will be outlined.

Translated title of the contributionThe role of angiotensin II inhibitors in hypertension: Clinical trials and guidelines
Original languageItalian
Pages (from-to)92-95
Number of pages4
JournalAnnali Italiani di Medicina Interna
Volume15
Issue number1
Publication statusPublished - 2000

ASJC Scopus subject areas

  • Internal Medicine

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