The Role of Biomarkers in Psychiatry

Madia Lozupone, Maddalena La Montagna, Francesca D'Urso, Antonio Daniele, Antonio Greco, Davide Seripa, Giancarlo Logroscino, Antonello Bellomo, Francesco Panza

Research output: Contribution to journalArticlepeer-review


Psychiatric illnesses are cognitive and behavioral disorders of the brain. At present, psychiatric diagnosis is based on DSM-5 criteria. Even if endophenotype specificity for psychiatric disorders is discussed, it is difficult to study and identify psychiatric biomarkers to support diagnosis, prognosis, or clinical response to treatment. This chapter investigates the innovative biomarkers of psychiatric diseases for diagnosis and personalized treatment, in particular post-genomic data and proteomic analyses.

Original languageEnglish
Pages (from-to)135-162
Number of pages28
JournalAdvances in Experimental Medicine and Biology
Publication statusPublished - Jan 1 2019


  • Biomarker
  • Bipolar disorder
  • Depressive disorder
  • Epigenetics
  • Lifestyle
  • Microbiota
  • Post-genomic diagnostics
  • Proteomics
  • Psychiatric disease
  • Schizophrenia

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)


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