The role of chemotherapy in the management of gastric cancer

Rocco De Vivo, Sandro Pignata, Raffaele Palaia, Valerio Parisi, Bruno Daniele

Research output: Contribution to journalArticlepeer-review


Despite a marked decline in the incidence of gastric carcinoma in Western countries, the majority of patients presents with advanced inoperable tumors. In this setting, usually the aim of therapy is palliation, with the exception of chemotherapy administered in the attempt to downstage the tumor and to facilitate potentially curative surgery in patients with locally advanced nonmetastatic disease. This review will focus on the use of chemotherapy for advanced gastric cancer and after curative surgery, providing an overview of future directions for clinical research: preoperative (neoadjuvant) systemic chemotherapy, intraperitoneal treatment, and newer drugs.

Original languageEnglish
Pages (from-to)364-371
Number of pages8
JournalJournal of Clinical Gastroenterology
Issue number4
Publication statusPublished - Jun 2000


  • Chemotherapy
  • Gastric cancer
  • Review

ASJC Scopus subject areas

  • Gastroenterology


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